Chemopreventive potential of green tea catechins in hepatocellular carcinoma

M Shimizu, Y Shirakami, H Sakai, M Kubota… - International journal of …, 2015 - mdpi.com
Hepatocellular carcinoma (HCC), which is a common malignancy worldwide, usually
develops in a cirrhotic liver due to hepatitis virus infection. Metabolic syndrome, which is …

Polyphenols as potential metabolism mechanisms regulators in liver protection and liver cancer prevention

S Li, S Yin, H Ding, Y Shao, S Zhou, W Pu… - Cell …, 2023 - Wiley Online Library
Background Liver cancer is one of the common malignancies. The dysregulation of
metabolism is a driver of accelerated tumourigenesis. Metabolic changes are well …

Epigenetic regulation by selected dietary phytochemicals in cancer chemoprevention

S Shukla, SM Meeran, SK Katiyar - Cancer letters, 2014 - Elsevier
The growing interest in cancer epigenetics is largely due to the reversible nature of
epigenetic changes which tend to alter during the course of carcinogenesis. Major …

Animal models of hepatocellular carcinoma prevention

RC Shankaraiah, L Gramantieri, F Fornari, S Sabbioni… - Cancers, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is a deadly disease and therapeutic efficacy in advanced
HCC is limited. Since progression of chronic liver disease to HCC involves a long latency …

Genetic and epigenetic targets of natural dietary compounds as anticancer agents

Q Shi, A Bishayee, D Bhatia - Epigenetics of cancer prevention, 2019 - Elsevier
Cancer is a heterogenous disease characterized by changes in the expression of multiple
genes caused by genetic alternations and epigenetic modifications. Studies of the changes …

[HTML][HTML] Current therapeutic modalities and chemopreventive role of natural products in liver cancer: Progress and promise

AK Singh, SV Singh, R Kumar, S Kumar… - World journal of …, 2023 - ncbi.nlm.nih.gov
Liver cancer is a severe concern for public health officials since the clinical cases are
increasing each year, with an estimated 5-year survival rate of 30%–35% after diagnosis …

Epigallocatechin-3-gallate in the prevention and treatment of hepatocellular carcinoma: experimental findings and translational perspectives

S Bimonte, V Albino, M Piccirillo, A Nasto… - Drug Design …, 2019 - Taylor & Francis
Hepatocellular carcinoma (HCC), a primary liver malignancy, is one of the deadliest cancers
worldwide. Despite orthotopic liver transplantation and hepatic resection representing the …

Cancer prevention by food factors through targeting signal transduction pathways

AM Bode, Z Dong - Nutrition, 2004 - Elsevier
Chemoprevention may be defined as the use of non-toxic substances, including many food
factors, to interfere with the process of cancer development or carcinogenesis before …

Epigenetic mechanisms in hepatocellular carcinoma: how environmental factors influence the epigenome

Z Herceg, A Paliwal - Mutation Research/Reviews in Mutation Research, 2011 - Elsevier
Epigenetic mechanisms maintain heritable changes in gene expression and chromatin
organization over many cell generations. Importantly, deregulated epigenetic mechanisms …

[HTML][HTML] The genetic and environmental basis of hepatocellular carcinoma

PA Farazi, RA DePinho - Discovery Medicine, 2009 - discoverymedicine.com
Liver cancer is among the most common malignancies, impacting significantly across all
societies worldwide. The lethal impact of this prevalent cancer is unlikely to change …