[HTML][HTML] Tfap2b acts in GABAergic neurons to control sleep in mice
Y Hu, H Bringmann - Scientific Reports, 2023 - nature.com
Sleep is a universal state of behavioral quiescence in both vertebrates and invertebrates
that is controlled by conserved genes. We previously found that AP2 transcription factors …
that is controlled by conserved genes. We previously found that AP2 transcription factors …
[HTML][HTML] TfAP-2 is required for night sleep in Drosophila
MM Kucherenko, V Ilangovan, B Herzig… - BMC neuroscience, 2016 - Springer
Background The AP-2 transcription factor APTF-1 is crucially required for developmentally
controlled sleep behavior in Caenorhabditis elegans larvae. Its human ortholog, TFAP …
controlled sleep behavior in Caenorhabditis elegans larvae. Its human ortholog, TFAP …
[HTML][HTML] Crucial role of TFAP2B in the nervous system for regulating NREM sleep
A Nakai, M Kashiwagi, T Fujiyama, K Iwasaki, A Hirano… - Molecular brain, 2024 - Springer
The AP-2 transcription factors are crucial for regulating sleep in both vertebrate and
invertebrate animals. In mice, loss of function of the transcription factor AP-2β (TFAP2B) …
invertebrate animals. In mice, loss of function of the transcription factor AP-2β (TFAP2B) …
Sleep architecture in mice is shaped by the transcription factor AP-2β
A Nakai, T Fujiyama, N Nagata, M Kashiwagi, A Ikkyu… - Genetics, 2020 - academic.oup.com
Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β | Genetics | Oxford
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Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …
[HTML][HTML] Knockdown of GABAA alpha3 subunits on thalamic reticular neurons enhances deep sleep in mice
Identification of mechanisms which increase deep sleep could lead to novel treatments
which promote the restorative effects of sleep. Here, we show that knockdown of the α3 …
which promote the restorative effects of sleep. Here, we show that knockdown of the α3 …
[HTML][HTML] An AP2 transcription factor is required for a sleep-active neuron to induce sleep-like quiescence in C. elegans
M Turek, I Lewandrowski, H Bringmann - Current Biology, 2013 - cell.com
Background Sleep is an essential behavior that is found in all animals that have a nervous
system. Neural activity is thought to control sleep, but little is known about the identity and …
system. Neural activity is thought to control sleep, but little is known about the identity and …
[HTML][HTML] Sleep-active neuron specification and sleep induction require FLP-11 neuropeptides to systemically induce sleep
M Turek, J Besseling, JP Spies, S König, H Bringmann - Elife, 2016 - elifesciences.org
Sleep is an essential behavioral state. It is induced by conserved sleep-active neurons that
express GABA. However, little is known about how sleep neuron function is determined and …
express GABA. However, little is known about how sleep neuron function is determined and …
[HTML][HTML] GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice
Sleep/wakefulness cycle is regulated by coordinated interactions between sleep-and
wakefulness-regulating neural circuitry. However, the detailed mechanism is far from …
wakefulness-regulating neural circuitry. However, the detailed mechanism is far from …
Genome-Wide Screen for Genes Involved in Caenorhabditis elegans Developmentally Timed Sleep
Abstract In Caenorhabditis elegans, Notch signaling regulates developmentally timed sleep
during the transition from L4 larval stage to adulthood (L4/A). To identify core sleep …
during the transition from L4 larval stage to adulthood (L4/A). To identify core sleep …
Conservation of sleep: insights from non-mammalian model systems
JE Zimmerman, N Naidoo, DM Raizen, AI Pack - Trends in neurosciences, 2008 - cell.com
The past 10 years have seen new approaches to elucidating genetic pathways regulating
sleep. The emerging theme is that sleep-like states are conserved in evolution, with similar …
sleep. The emerging theme is that sleep-like states are conserved in evolution, with similar …