Genome-wide association studies have shown that the far majority of disease-associated
variants reside in the non-coding regions of the genome, suggesting that gene regulatory …

Genome-wide association studies (GWASs) provide a key foundation for elucidating the
genetic underpinnings of common polygenic diseases. However, these studies have …

Genome-wide association studies (GWAS) have found the majority of disease-associated
variants to be non-coding. Major efforts into the charting of the non-coding regulatory …

During the past 12 years, genome-wide association studies (GWASs) have uncovered
thousands of genetic variants that influence risk for complex human traits and diseases. Yet …

A central goal in human genetics is the identification of variants and genes that influence the
risk of polygenic diseases. In the past decade, genome-wide association studies (GWAS) …

Genome-wide association studies have successfully identified numerous loci at which
common variants influence disease risk or quantitative traits. Despite these successes, the …

Genome-wide association studies (GWAS) have identified a large number of disease-
associated SNPs, but in few cases the functional variant and the gene it controls have been …

Despite accumulating evidence implicating noncoding variants in human diseases,
unraveling their functionality remains a significant challenge. Systematic annotations of the …

Thousands of common genetic variants in the human population have been associated with
disease risk and phenotypic variation by genome-wide association studies (GWAS) …

Genome-wide association studies (GWAS) have identified more than 8900 genetic variants,
mainly single-nucleotide polymorphisms (SNPs), associated with hundreds of human traits …