Yttrium-90 microspheres: radiation therapy for unresectable liver cancer

R Salem, KG Thurston, BI Carr, JE Goin… - Journal of Vascular and …, 2002 - Elsevier
Hepatocellular carcinoma (HCC) constitutes a difficult health challenge because of its poor
prognosis and limited treatment options. Most available therapies are used only for …

Physical aspects of yttrium‐90 microsphere therapy for nonresectable hepatic tumors

M Sarfaraz, AS Kennedy, ZJ Cao, GD Sackett… - Medical …, 2003 - Wiley Online Library
Administration of yttrium‐90 microspheres via the hepatic artery is an attractive approach to
selectively deliver therapeutic doses of radiation to liver malignancies. This procedure …

Current role of selective internal irradiation with yttrium-90 microspheres in the management of hepatocellular carcinoma: a systematic review

WY Lau, ECH Lai, TWT Leung - International Journal of Radiation …, 2011 - Elsevier
PURPOSE: This article reviews the role of selective internal irradiation (SIR) with yttrium-90
(90Y) microspheres for hepatocellular carcinoma (HCC). METHODS AND MATERIALS …

A phase I dose escalation trial of yttrium‐90 microspheres in the treatment of primary hepatocellular carcinoma

FA Shepherd, LE Rotstein, S Houle, TCK Yip, K Paul… - Cancer, 1992 - Wiley Online Library
Methods. Ten patients with primary hepatocellular carcinoma were treated with intraarterial
instillation of yttrium‐90 (Y‐90) microspheres, including eight men and two women (median …

Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: factors associated with liver toxicities

JE Goin, R Salem, BI Carr, JE Dancey… - Journal of Vascular and …, 2005 - Elsevier
PURPOSE: Intraarterial injection of yttrium 90 microspheres (TheraSpheres) is used in the
treatment of hepatocellular carcinoma (HCC). This article presents an analysis of the …

Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications

R Murthy, R Nunez, J Szklaruk, W Erwin, DC Madoff… - Radiographics, 2005 - pubs.rsna.org
Management of hepatic malignancies is a ubiquitous medical problem. Surgical resection of
primary or metastatic liver cancer, with or without adjuvant chemotherapy, is the most …

Radioembolization for hepatocellular carcinoma using Yttrium-90 microspheres: a comprehensive report of long-term outcomes

R Salem, RJ Lewandowski, MF Mulcahy, A Riaz… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) has limited treatment options;
long-term outcomes following intra-arterial radiation are unknown. We assessed clinical …

Yttrium-90 radioembolization of hepatocellular carcinoma and metastatic disease to the liver

RJ Lewandowski, R Salem - Seminars in interventional …, 2006 - thieme-connect.com
ABSTRACT Yttrium-90 (90 Y) radioembolization is a catheter-based therapy that delivers
internal radiation to hepatic tumors in the form of microspheres. 90 Y can be delivered to the …

Radioembolization of yttrium-90 microspheres for hepatic malignancy

R Murthy, P Kamat, R Nunez… - Seminars in …, 2008 - thieme-connect.com
The liver represents a frequent site for primary and secondary neoplasia. Cytoreductive
techniques positively influence the outcome of disease progression in these patients …

Treatment of nonresectable hepatocellular carcinoma with intrahepatic 90Y-microspheres

JE Dancey, FA Shepherd, K Paul… - Journal of nuclear …, 2000 - Soc Nuclear Med
Treatment for nonresectable hepatocellular carcinoma (HCC) is palliative. The relatively
greater arteriolar density of hepatic tumors compared with normal liver suggests that …