DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma
S Udali, P Guarini, A Ruzzenente, A Ferrarini… - Clinical …, 2015 - Springer
Background Alcohol is a well-known risk factor for hepatocellular carcinoma (HCC), but the
mechanisms underlying the alcohol-related hepatocarcinogenesis are still poorly …
mechanisms underlying the alcohol-related hepatocarcinogenesis are still poorly …
Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake
MP Lambert, A Paliwal, T Vaissière, I Chemin… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is one of the most frequent
human cancers and a major cause of cancer-related death worldwide. The major risk factors …
human cancers and a major cause of cancer-related death worldwide. The major risk factors …
[HTML][HTML] Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis
RA Hlady, RL Tiedemann, W Puszyk, I Zendejas… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the second most common cause of cancer deaths
worldwide. Deregulated DNA methylation landscapes are ubiquitous in human cancers …
worldwide. Deregulated DNA methylation landscapes are ubiquitous in human cancers …
Sex and race-related DNA methylation changes in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the sixth most common cancer and fourth leading cause
of cancer-related death worldwide. The number of HCC cases continues to rise despite …
of cancer-related death worldwide. The number of HCC cases continues to rise despite …
[PDF][PDF] Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma
We aimed to identify the specific subset of tumor suppressor genes (TSGs) that are
methylation‐silenced during the earliest steps of hepatocarcinogenesis, and to further …
methylation‐silenced during the earliest steps of hepatocarcinogenesis, and to further …
Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors
Background Hepatocellular carcinoma (HCC) is characterized by late detection and fast
progression, and it is believed that epigenetic disruption may be the cause of its molecular …
progression, and it is believed that epigenetic disruption may be the cause of its molecular …
[PDF][PDF] DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma
A Villanueva, A Portela, S Sayols, C Battiston… - …, 2015 - Wiley Online Library
Epigenetic deregulation has emerged as a driver in human malignancies. There is no clear
understanding of the epigenetic alterations in hepatocellular carcinoma (HCC) and of the …
understanding of the epigenetic alterations in hepatocellular carcinoma (HCC) and of the …
Elucidating the landscape of aberrant DNA methylation in hepatocellular carcinoma
Background Hepatocellular carcinoma (HCC) is one of the most common cancers and
frequently presents with an advanced disease at diagnosis. There is only limited knowledge …
frequently presents with an advanced disease at diagnosis. There is only limited knowledge …
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma
DF Calvisi, S Ladu, A Gorden, M Farina… - The Journal of …, 2007 - Am Soc Clin Investig
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, accounting for
an estimated 600,000 deaths annually. Aberrant methylation, consisting of DNA …
an estimated 600,000 deaths annually. Aberrant methylation, consisting of DNA …
Epigenetic changes affecting the development of hepatocellular carcinoma
E Wolinska, M Skrzypczak - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma is a life-threatening disease. Despite many
efforts to understand the exact pathogenesis and the signaling pathways involved in its …
efforts to understand the exact pathogenesis and the signaling pathways involved in its …
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