The nuclear structure changes during the differentiation from growing to infective stages of
Trypanosoma cruzi. As histone modifications have been correlated with structural and …

Phosphorylation of histone H1 is intimately related to the cell cycle progression in higher
eukaryotes, reaching maximum levels during mitosis. We have previously shown that in the …

Histone H1 of most eukaryotes is phosphorylated during the cell cycle progression and
seems to play a role in the regulation of chromatin structure, affecting replication and …

Trypanosoma cruzi chromatin is not condensed in chromosomes during mitosis. In previous
studies a characteristic H 1 was not found in SDS or in acid-urea-PAGE. Consequently, it …

Histones of trypanosomes are quite divergent when compared to histones of most
eukaryotes. Nevertheless, the histone H4 of Trypanosoma cruzi, the protozoan that causes …

Several biological processes in Trypanosoma brucei are affected by chromatin structure,
including gene expression, cell cycle regulation, and life-cycle stage differentiation. In …

Histone tails provide sites for a variety of post-translational modifications implicated in the
control of gene expression and chromatin assembly. As both histones and control of gene …

Trypanosoma cruzi is the etiological agent of Chagas. Although the nuclear chromatin of this
parasite is organized in the form of nucleosome filaments, its chromatin is physically and …

The histone H4 from Trypanosomatids diverged from other eukaryotes in the N-terminus, a
region that undergoes post-translation modifications involved in the control of gene …

Histones are well-conserved proteins that form the basic structure of chromatin in eukaryotes
and undergo several post-translational modifications, which are important for the control of …