Abstract Mesenchymal Stem Cells (MSC) are multipotent non-hematopoietic progenitor cells
with an extensive proliferation potential and ability to differentiate into various cell types …

Bone possesses the intrinsic regeneration capacity as part of the repair process in response
to injury, during skeletal development or continuous remodeling throughout adult life …

The enhancement of bone regeneration with biological agents including osteogenic growth
factors and mesenchymal stem cells (MSCs) is becoming a clinical reality. Many exciting …

There is growing interest in the use of mesenchymal stem cells for bone repair. As a major
reason for normal bone remodeling is the removal of fatigue microcracks, advances in our …

Bone tissue engineering using human mesenchymal stem cells (hMSCs) is a
multidisciplinary field that aims to treat patients with trauma, spinal fusion and large bone …

The loss of bone mass observed in aging enhances the risk of fractures. The process of
bone repair in aging is slow and limited due to reduced activity of the osteoblasts. Bone …

The most important features that determine the vital role of bone include: a) a continuous
supply of calcium, which is indispensible for every cell of the entire organism at all times …

The tremendous capacity of bone to regenerate is indicative of the presence of stem cells
with the capability, by definition, to self-renew as well as to give rise to daughter cells. These …

With the ageing population, musculoskeletal conditions are becoming more inherent.
Delayed union is defined as a slower than normal fracture healing response, with no healing …

Bone is a highly vascularized tissue reliant on the close spatial and temporal association
between blood vessels and bone cells. Therefore, cells that participate in vasculogenesis …