Mesenchymal stem cells (MSC) are a group of cells present in bone-marrow stroma and the
stroma of various organs with the capacity for mesoderm-like cell differentiation into, for …

The use of stem cells in regenerative medicine, including tissue engineering and
transplantation, has generated a great deal of enthusiasm. Mesenchymal stromal/stem cells …

Background Human mesenchymal stem cells (hMSCs) are pluripotent cells that can
differentiate to various mesenchymal cell types. Recently, a method to isolate hMSCs from …

Today, surgical intervention remains the mainstay of treatment to intervene upon a multitude
of skeletal deficits and defects attributable to congenital malformations, oncologic resection …

While small bone defects heal spontaneously, large bone defects need surgical intervention
for bone transplantation. Autologous bone grafts are the best and safest strategy for bone …

Bones are an important component of vertebrates; they grow explosively in early life and
maintain their strength throughout life. Bones also possess amazing capabilities to repair …

A technology has been developed to isolate a developmentally and phenotypically
homogeneous population of pluripotent human mesenchymal stem cells (hMSCs) from adult …

Marrow stromal cells (MSC) are thought to be stem cells with osteogenic potential and
therefore responsible for the repair and maintenance of the skeleton. Age related bone loss …

Bone structural integrity and shape are maintained by removal of old matrix by osteoclasts
and in-situ synthesis of new bone by osteoblasts. These cells comprise the basic …

Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …