Fast optical signals in the peripheral nervous system

Y Tong, JM Martin, A Sassaroli… - Journal of …, 2006 - spiedigitallibrary.org
We present a study of the near-infrared optical response to electrical stimulation of
peripheral nerves. The sural nerve of six healthy subjects between the ages of 22 and 41 …

Dynamic physiological modeling for functional diffuse optical tomography

SG Diamond, TJ Huppert, V Kolehmainen… - Neuroimage, 2006 - Elsevier
Diffuse optical tomography (DOT) is a noninvasive imaging technology that is sensitive to
local concentration changes in oxy-and deoxyhemoglobin. When applied to functional …

Design and evaluation of a continuous-wave diffuse optical tomography system

AM Siegel, JJA Marota, DA Boas - Optics express, 1999 - opg.optica.org
Diffuse optical tomography (DOT) can image spatial variations in highly scattering optical
media. We have built an inexpensive and portable continuous-wave DOT system containing …

Optimization of the method for assessment of brain perfusion in humans using contrast-enhanced reflectometry: multidistance time-resolved measurements

D Milej, D Janusek, A Gerega… - Journal of …, 2015 - spiedigitallibrary.org
The aim of the study was to determine optimal measurement conditions for assessment of
brain perfusion with the use of optical contrast agent and time-resolved diffuse reflectometry …

Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury

C Crouzet, T Phan, RH Wilson, TJ Shin… - …, 2023 - spiedigitallibrary.org
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …

Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data

S Brigadoi, P Phan, D Highton, S Powell… - …, 2017 - spiedigitallibrary.org
In diffuse optical tomography (DOT), overlapping and multidistance measurements are
required to reconstruct depth-resolved images of oxy-(HbO 2) and deoxy-(HHb) hemoglobin …

Functional neuroimaging: optical approaches

A Villringer - Optical Imaging of Brain Function and Metabolism 2 …, 1997 - Springer
Optical methods assess different types of light tissue interactions such as light absorption,
fluorescence, phosphoresence, scattering, and Doppler shift. In this article, it is reviewed …

Assessment of inflow and washout of indocyanine green in the adult human brain by monitoring of diffuse reflectance at large source-detector separation

A Liebert, P Sawosz, D Milej… - … of biomedical optics, 2011 - spiedigitallibrary.org
Recently, it was shown in measurements carried out on humans that time-resolved near-
infrared reflectometry and fluorescence spectroscopy may allow for discrimination of …

Diffuse optical imaging using spatially and temporally modulated light

TD O'Sullivan, AE Cerussi, DJ Cuccia… - … of biomedical optics, 2012 - spiedigitallibrary.org
The authors describe the development of diffuse optical imaging (DOI) technologies,
specifically the use of spatial and temporal modulation to control near infrared light …

Monitoring hemodynamic and morphologic responses to closed head injury in a mouse model using orthogonal diffuse near-infrared light reflectance spectroscopy

D Abookasis, A Shochat… - Journal of Biomedical …, 2013 - spiedigitallibrary.org
The authors' aim is to assess and quantitatively measure brain hemodynamic and
morphological variations during closed-head injury (CHI) in mice using orthogonal diffuse …