Inflammation has long been thought to contribute to the development of cancer; however
there is also clear evidence that the immune system can recognize and eliminate cancer …

Central to the development of cancer are genetic changes that endow these “cancer cells”
with many of the hallmarks of cancer, such as self-sufficient growth and resistance to anti …

It was Aulus Cornelius Celsus, a physician in first-century Rome, who first defined
inflammation as calor (heat), dolor (pain), rubor (redness), and tumor (swelling). However, it …

State of the Art: Mounting evidence indicates a link between inflammation and cancer.
However, the molecular mechanism (s) remains unclear. Indeed, although preclinical and …

As early as the 19th century, inflammation has been perceived to have a link with cancer but
this perception has waned through the passing of time. In recent years however a renewed …

Purpose Cancer cells, despite stemming from the own cells of their host, usually elicit an
immune response. This response usually enables elimination of cancer at its earliest stages …

Inflammatory mediators in tumor microenvironment influence cancer occurrence, growth and
metastasis through complex signaling networks. Excessive inflammation is closely …

Inflammatory responses play decisive roles at different stages of tumor development,
including initiation, promotion, malignant conversion, invasion, and metastasis. Inflammation …

Epidemiological and experimental data suggest a close connection between inflammation
and tumorigenesis. Solid tumors are typically infiltrated with immune cells and inflammation …

It has been established that cancer can be promoted and/or exacerbated by inflammation
and infections. Indeed, chronic inflammation orchestrates a tumor-supporting …