Optical imaging and modulation of neurovascular responses

K Masamoto, A Vazquez - Journal of Cerebral Blood Flow & …, 2018 - journals.sagepub.com
The cerebral microvasculature consists of pial vascular networks, parenchymal descending
arterioles, ascending venules and parenchymal capillaries. This vascular …

Neurovascular coupling: in vivo optical techniques for functional brain imaging

LD Liao, V Tsytsarev, I Delgado-Martínez, ML Li… - Biomedical engineering …, 2013 - Springer
Optical imaging techniques reflect different biochemical processes in the brain, which is
closely related with neural activity. Scientists and clinicians employ a variety of optical …

Cerebral microvascular network geometry changes in response to functional stimulation

L Lindvere, R Janik, A Dorr, D Chartash, B Sahota… - Neuroimage, 2013 - Elsevier
The cortical microvessels are organized in an intricate, hierarchical, three-dimensional
network. Superimposed on this anatomical complexity is the highly complicated signaling …

Functional evaluation of hemodynamic response during neural activation using optical microangiography integrated with dual-wavelength laser speckle imaging

J Qin, L Shi, H Wang, R Reif… - Journal of Biomedical …, 2014 - spiedigitallibrary.org
Evaluation of spatiotemporal hemodynamic and metabolic responses during neural
activation is crucial in studying brain function. We explore the use of a noninvasive …

Toward an integrative neurovascular framework for studying brain networks

J Guilbert, A Légaré, P De Koninck… - …, 2022 - spiedigitallibrary.org
Brain functional connectivity based on the measure of blood oxygen level-dependent
(BOLD) functional magnetic resonance imaging (fMRI) signals has become one of the most …

Noninvasive functional imaging of human brain using light

DA Benaron, SR Hintz, A Villringer… - Journal of Cerebral …, 2000 - journals.sagepub.com
Analysis of photon transit time for low-power light passing into the head, and through both
skull and brain, of human subjects allowed for tomographic imaging of cerebral hemoglobin …

High-speed vascular dynamics of the hemodynamic response

BR Chen, MB Bouchard, AFH McCaslin, SA Burgess… - Neuroimage, 2011 - Elsevier
While a range of cellular mechanisms have been proposed to underlie control of
neurovascular coupling, a comprehensive, reconciliatory model has yet to be determined …

Quantitative estimates of stimulation-induced perfusion response using two-photon fluorescence microscopy of cortical microvascular networks

LV Chinta, L Lindvere, A Dorr, B Sahota, JG Sled… - Neuroimage, 2012 - Elsevier
Functional hyperemia, or the increase in focal perfusion elicited by neuronal activation, is
one of the primary functions of the neurovascular unit and a hallmark of healthy brain …

Cerebral vascular structure in the motor cortex of adult mice is stable and is not altered by voluntary exercise

RH Cudmore, SE Dougherty… - Journal of Cerebral …, 2017 - journals.sagepub.com
The cerebral vasculature provides blood flow throughout the brain, and local changes in
blood flow are regulated to match the metabolic demands of the active brain regions. This …

In vivo imaging for neurovascular disease research

JH Yoon, Y Jeong - Archives of pharmacal research, 2019 - Springer
Connections between various cell types in the brain enable cognitive function. The
neurovascular unit is a structure composed of different cell types that regulate neurovascular …