In the past two decades it has become clear that in addition to antigen presentation and
antibody production B cells play prominent roles in immune regulation. While B cell-derived …

Over the last decade it has become evident that in addition to producing antibody, B cells
activate the immune system by producing cytokines and via antigen presentation. In …

B cells include immune-suppressive fractions, called regulatory B cells (Bregs), which
regulate inflammation primarily through an interleukin 10 (IL-10)-mediated inhibitory …

B cells are regarded for their capacity to produce antibody. However, recent advances in B
cell biology have capitalized on old findings and demonstrated that B cells also release a …

Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …

Over the past decade, studies have identified subset of B cells, which play suppressive
functions in additions to the conventional functions of B cells: antigen processing and …

Regulatory B (Breg) cells are important regulators of immune responses and in recent years
our understanding of their phenotypical and functional characteristics has improved …

Regulatory B cells (Bregs) modulate immune responses predominantly, although not
exclusively, via the release of IL-10. The importance of human Bregs in the maintenance of …

Compelling evidence has demonstrated that IL-10-producing regulatory B cells (Bregs) are
specialized to suppress immune responses and control various immunopathologies …

The aim of the following review is to shed light on the putative role of regulatory B cells
(Bregs) in various human diseases and highlight their potential prognostic and therapeutic …