Characterization of Cl-HCO3 exchange in basolateral membrane of rat distal colon

M Ikuma, J Geibel, HJ Binder… - American Journal of …, 2003 - journals.physiology.org
Sodium-independent Cl movement (ie, Cl-anion exchange) has not previously been
identified in the basolateral membranes of rat colonic epithelial cells. The present study …

Ammonium effects on colonic Cl- secretion: anomalous mole fraction behavior

RT Worrell, J Oghene… - American Journal of …, 2004 - journals.physiology.org
A significant amount of ammonium () is absorbed by the colon. The nature of effects on
transport and transport itself in colonic epithelium is poorly understood. The goal of this …

Mechanism of cholinergic regulation of electrolyte transport in rat colon in vitro

TW Zimmerman, JW Dobbins… - American Journal of …, 1982 - journals.physiology.org
Cholinergic agonists inhibit sodium and chloride absorption in the intestine and often
produce secretion. To determine the mechanism of cholinergic regulation of intestinal …

Cholinergic ion secretion in human colon requires coactivation by cAMP

M Mall, M Bleich, M Schurlein, J Kuhr… - American Journal …, 1998 - journals.physiology.org
Cl− secretion in the colon can be activated by an increase of either intracellular Ca2+ or
cAMP. In this study we examined a possible interdependence of the two second-messenger …

Segment-specific effects of epinephrine on ion transport in the colon of the rat

S Hörger, G Schultheiß… - American Journal of …, 1998 - journals.physiology.org
The effect of epinephrine on transport of K+, Na+, Cl−, and HCO 3− across the rat colon was
studied using the Ussing chamber technique. Epinephrine (5× 10− 6 mol/l) induced a …

[PDF][PDF] Disturbance of cholinergic regulation of electrogenic epithelial ion transport in the inflamed colon

T Yamamoto, Y Katuki, M Kadowaki - Digestive Disease Week, 2010 - academia.edu
The colon has mechanisms for both absorbing and secreting water and electrolytes through
the epithelial transport systems. These transport systems are considered to play important …

Prostanoids stimulate K secretion and Cl secretion in guinea pig distal colon via distinct pathways

DR Halm, ST Halm - American Journal of Physiology …, 2001 - journals.physiology.org
Short-circuit current (I sc) and transepithelial conductance (G t) were measured in guinea pig
distal colonic mucosa isolated from submucosa and underlying muscle layers. Indomethacin …

Basolateral Ca2+‐dependent K+‐channels play a key role in Cl—secretion induced by taurodeoxycholate from colon mucosa

A Moschetta, P Portincasa, L Debellis… - Biology of the …, 2003 - Wiley Online Library
The diarrhea associated with malabsorption of bile salts such as the secondary hydrophobic
taurodeoxycholate (TDC) may be partly explained by the TDC‐induced increase in colon …

Rabbit proximal colon: a distinct transport epithelium

JH Sellin, R DeSoignie - American Journal of Physiology …, 1984 - journals.physiology.org
Rabbit proximal colon (PC), examined in vitro, exhibits transport characteristics distinct from
distal colon. Unlike distal colon, PC does not demonstrate amiloride-inhibitable electrogenic …

Palmatine, a protoberberine alkaloid, inhibits both Ca2+‐ and cAMP‐activated Cl secretion in isolated rat distal colon

DZ Wu, JY Yuan, HL Shi, ZB Hu - British journal of …, 2008 - Wiley Online Library
Background and purpose: The protoberberine alkaloid berberine has been reported to
inhibit colonic Cl− secretion. However, it is not known if other protoberberine alkaloids share …