Background The first target of antimicrobial peptides (AMPs) is the bacterial membrane. In
the case of Gram-negative bacteria this is the outer membrane (OM), the lipid composition of …

Abstract Hypothesis Antimicrobial peptides (AMPs) kill microorganisms by causing structural
damage to bacterial membranes. Different microorganisms often require a different type and …

Many antimicrobial peptides (AMPs) target bacterial membranes and they kill bacteria by
causing structural disruptions. One of the fundamental issues however lies in the selective …

Lipopolysaccharides (LPSs) play a dual role as target and as effector molecules. The
knowledge of the LPS-induced activation of human immune cells is increasing; however …

Interactions of calcium (Ca2+) and zinc (Zn2+) cations with biomimetic membranes made of
dipalmitoylphosphatidylcholine (DPPC) were studied by small angle neutron diffraction …

The indiscriminate use of conventional antibiotics is leading to an increase in the number of
resistant bacterial strains, motivating the search for new compounds to overcome this …

Many antimicrobial peptides (AMPs) are cationic host defence peptides (HDPs) that interact
with microbial membranes. This ability may lead to implementation of AMPs as therapeutics …

Antimicrobial peptides (AMPs) are produced by almost all living organisms as a component
of their immune system representing the first line weapons against infective agents. During …

Supported lipid bilayers are used as a convenient model cell membrane system to study
biologically important molecule–lipid interactions in situ. However, the lipid bilayer models …

The bacterial membrane represents an attractive target for the design of new antibiotics to
combat widespread bacterial resistance. Understanding how antimicrobial peptides (AMPs) …