Migraine is a complex, debilitating neurovascular disorder, typically characterized by
recurring, incapacitating attacks of severe headache often accompanied by nausea and …

The treatment and prevention of migraine within the last decade has become largely
pharmacological. While there is little doubt that the advent of drugs (eg triptans) has helped …

Background.—The serotonergic system has a significant role in the pathophysiology and
pharmacology of migraine. Objective.—To study the association between the occurrence of …

Aims: Migraine has a wide clinical spectrum. Our aim was to group information on migraine
characteristics into meaningful components and to identify key components of the migraine …

Migraine is a complex disorder caused by a combination of genetic and environmental
factors. Although family and twin studies show that there is a genetic component in migraine …

Migraine is a debilitating neurological disorder characterized by recurrent attacks of severe
headache. The disorder is highly prevalent, affecting approximately 12% of Caucasian …

Migraine is a highly disabling primary headache associated with a high socioeconomic
burden and a generally high prevalence. The clinical management of migraine remains a …

Allelic variation of the human serotonin transporter gene (HSERT), a highly plausible
candidate gene for susceptibility to migraine, was investigated in 266 individuals with …

CAHILL & MURPHY 1993), using family study data, found no evidence for the co-
segregation of these disorders. The relatives of probands with depression alone did not …

Integration of genetic, phenotypic and epigenetic data will help to identify the biological
mechanisms by which genetic factors contribute to migraine pathogenesis. Recent studies …