[HTML][HTML] Red blood cell deformability during storage: towards functional proteomics and metabolomics in the Blood Bank

JCA Cluitmans, MR Hardeman, S Dinkla… - Blood …, 2012 - ncbi.nlm.nih.gov
During storage, RBCs undergo various metabolic, structural and morphological changes,
the so-called storage lesions1. The acceptable extent of the metabolic changes forms a …

Insights into red blood cell storage lesion: toward a new appreciation

MH Antonelou, J Seghatchian - Transfusion and Apheresis Science, 2016 - Elsevier
Red blood cell storage lesion (RSL) is a multifaceted biological phenomenon. It refers to
deterioration in RBC quality that is characterized by lethal and sub-lethal, reversible and …

Targeted quantitative phosphoproteomic analysis of erythrocyte membranes during blood bank storage

S Rinalducci, V Longo, LR Ceci… - Journal of Mass …, 2015 - Wiley Online Library
One of the hallmarks of blood bank stored red blood cells (RBCs) is the irreversible
transition from a discoid to a spherocyte‐like morphology with membrane perturbation and …

Deformability of stored red blood cells

G Barshtein, I Pajic-Lijakovic, A Gural - Frontiers in Physiology, 2021 - frontiersin.org
Red blood cells (RBCs) deformability refers to the cells' ability to adapt their shape to the
dynamically changing flow conditions so as to minimize their resistance to flow. The high red …

[HTML][HTML] Temporal sequence of major biochemical events during blood bank storage of packed red blood cells

BS Karon, CM Van Buskirk, EA Jaben, JD Hoyer… - Blood …, 2012 - ncbi.nlm.nih.gov
Background. We used sensitive spectroscopic techniques to measure changes in Band 3
oligomeric state during storage of packed red blood cells (RBC); these changes were …

Survival of red blood cells after transfusion: processes and consequences

GJ Bosman - Frontiers in physiology, 2013 - frontiersin.org
The currently available data suggest that efforts toward improving the quality of red blood
cell (RBC) blood bank products should concentrate on:(1) preventing the removal of a …

[HTML][HTML] Cumulative erythrocyte damage in blood storage and relevance to massive transfusions: selective insights into serial morphological and biochemical findings

JS Putter, J Seghatchian - Blood transfusion, 2017 - ncbi.nlm.nih.gov
Elucidating the precise mechanisms of cumulative red cell damages during storage and the
potential harmful consequences after transfusion are achievable by exacting laboratory …

Donor‐variation effect on red blood cell storage lesion: A close relationship emerges

VL Tzounakas, AG Kriebardis… - PROTEOMICS …, 2016 - Wiley Online Library
Although the molecular pathways leading to the progressive deterioration of stored red
blood cells (RBC storage lesion) and the clinical relevance of storage‐induced changes …

Red blood cell storage and cell morphology

B Blasi, A D'alessandro, N Ramundo… - Transfusion …, 2012 - Wiley Online Library
Aim: In this study, we performed weekly assessment of morphology‐related parameters
through monitoring of CPD‐SAGM leuco‐filtered erythrocyte concentrates from blood …

Decrease in red blood cell deformability is associated with a reduction in RBC-NOS activation during storage

M Grau, P Friederichs, S Krehan… - Clinical …, 2015 - content.iospress.com
During storage, red blood cells (RBC) become more susceptible to hemolysis and it has also
been shown that RBC deformability, which is influenced by RBC nitric oxide synthase (RBC …