BACKGROUND: It has been suggested that red blood cell (RBC) senescence is accelerated
under blood bank conditions, although neither protein profile of RBC aging nor the impact of …

Background Red blood cells collected in citrate-phosphate-dextrose can be stored for up to
42 days at 4 C in saline-adenine-glucose-mannitol additive solution. During this controlled …

Usually packed red blood cells (pRBCs) require specific conditions in storage procedures to
ensure the maximum shelf life of up to 42 days in 2–6° C. However, molecular and …

Background Studies are currently under way examining whether the age of stored red blood
cells (RBCs) affects clinical outcome in transfusion recipients. The effects of storage duration …

Background Storage of red blood cells at 4 C is associated with deleterious metabolic and
biochemical changes, collectively referred to as “storage lesions”. Lipid peroxidation of the …

BACKGROUND: Membrane‐associated carbohydrate changes act as signals for removal of
senescent and damaged red blood cells (RBCs) from the circulation and could play a role in …

Background Characteristics of red blood cells (RBCs) are influenced by donor variability.
This study assessed quality and metabolomic variables of RBC subpopulations of varied …

Background. Transfusion of blood components may increase the risk of complications in
relation to surgery. During storage, red blood cells (RBCs) undergo structural and functional …

The red blood cells (RBCs) aging process is considered as an issue of special scientific and
clinical interest. It represents a total of unidirectional, timedependent but not-necessarily …

Aims Numerous studies have suggested that transfusion of red blood cells (RBCs) stored
over a long period of time may induce harmful effects due to storage-induced lesions …