Solid tumors consist of neoplastic cells, non-malignant stromal cells, and migratory
hematopoietic cells. Complex interactions between the cell types in this microenvironment …

Inflammatory conditions in selected organs increase the risk of cancer. An inflammatory
component is present also in the microenvironment of tumours that are not epidemiologically …

Chronic inflammation typical to various chronic diseases is associated with
immunosuppression, mediated primarily by immature myeloid-derived suppressor cells …

Evidence has emerged in the last two decades that at the molecular level most chronic
diseases, including cancer, are caused by a dysregulated inflammatory response. The …

Chronic inflammation is a well-recognized tumor-enabling capability, which allows nascent
tumors to escape immunosurveillance. A number of soluble and cellular inflammatory …

Inflammatory cells and mediators are an essential component of the tumor
microenvironment (TME). Figure 1 provides a schematic representation of pathways …

There is evidence supporting the hypothesis that inflammation participates in providing
conditions that lead to cancer. An unresolved inflammation due to any failure in the precise …

Several recent studies have identified nuclear factor-κB as a key modulator in driving
inflammation to cancers. Besides this transcription factor, essential in regulating …

Chronic infections, obesity, alcohol, tobacco, radiation, environmental pollutants, and high-
calorie diet have been recognized as major risk factors for the most common types of cancer …

Inflammation is triggered when innate immune cells detect infection or tissue injury.
Surveillance mechanisms involve pattern recognition receptors (PRRs) on the cell surface …