The coordination of spontaneous brain activity is widely enhanced relative to compensation
activity in Parkinson's disease (PD) with tremor; however, the associated topological …

Motor phenotypes of Parkinson's disease (PD) are recognized to have different prognosis
and therapeutic response, but the neural basis for this clinical heterogeneity remains largely …

Background: Neuronal loss in Parkinson's Disease (PD) leads to widespread neural network
dysfunction. While graph theory allows for analysis of whole brain networks, patterns of …

Abnormalities in functional connectivity networks are associated with sensorimotor networks
in Parkinson's disease (PD) based on group-level mapping studies, but these results are …

Mild cognitive impairment in Parkinson's disease (PD-M) is related to a high risk of
dementia. This study explored the whole-brain functional networks in early-stage PD-M …

Depression is the most common non-motor symptom accompanying Parkinson's disease
(PD) with high prevalence but unclear pathophysiological mechanism. Relatively little is …

A wide range of disorders are thought to arise from dysfunction in brain circuitry (Bonelli and
Cummings, 2007). These pathological circuits are not directly appreciated on routinely …

Objective To investigate the topographic arrangement and strength of whole-brain white
matter (WM) structural connectivity in patients with early-stage drug-naive Parkinson disease …

There is growing interest in the potential of neuroimaging to help develop non-invasive
biomarkers in neurodegenerative diseases. In this study, connection-wise patterns of …

Resting-state functional magnetic resonance imaging (RS-fMRI) studies have been
extensively applied to analyze the pathophysiology of neurodegenerative disorders such as …