Objective To examine the putative regulatory role of TwDXR in terpenoid biosynthesis and
terpenoid biosynthetic pathway-related gene expression, through overexpression and RNA …

Abstract Tripterygium wilfordii 3-hydroxy-3-methylglutaryl coenzyme-A reductase (TwHMGR)
is an important regulation site in terpenoids metabolic pathway in cytoplasm which is the first …

1-Deoxy-d-xylulose-5-phosphate synthase (DXS) and 1-deoxy-d-xylulose-5-phosphate
reductoisomerase (DXR) genes are the key enzyme genes of terpenoid biosynthesis but still …

The aim of this study was to verify the effects of TwIDI (GenBank: KT279355. 1) on triptolide
and celastrol accumulation in the biosynthesis of terpenoids in Tripterygium wilfordii and the …

MCT is an important key enzyme in the terpenoid biosynthesis in MEP pathway. In this study,
Gateway technology was used to construct RNAi vector of TwMCT, and a vector fragment …

Hydroxy-3-methylglutaryl-CoA synthase (HMGS) is the first committed enzyme in the MVA
pathway and involved in the biosynthesis of terpenes in Tripterygium wilfordii. The full-length …

1‐Deoxy‐d‐xylulose‐5‐phosphate synthase (DXS) is the first enzyme in the plant 2‐C‐
methyl‐d‐erythritol 4‐phosphate (MEP) pathway of terpenoid synthesis. TwDXS is a …

Tripterygium wilfordii (Celastraceae) is a medicinal plant with anti‐inflammatory and
immunosuppressive properties. Identification of a vast array of unusual sesquiterpenoids …

Tripterygium wilfordii Hook. f. is the traditional medicinal plants in China. Triptolide,
wilforgine, and wilforine are the bioactive compounds in T. wilfordii. In this study, the …