Background Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to
guide efficient tuberculosis control strategies. Traditional strain typing lacks sufficient …

Background. Whole-genome sequencing (WGS) is increasingly used in molecular-
epidemiological investigations of bacterial pathogens, despite cost-and time-intensive …

Background Tuberculosis (TB) remains a serious public health threat worldwide.
Theoretically ultimate resolution of whole genome sequencing (WGS) for Mycobacterium …

The emergence of whole genome sequencing (WGS) technologies as primary research
tools has allowed for the detection of genetic diversity in Mycobacterium tuberculosis (Mtb) …

Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been used to trace
the transmission of M. tuberculosis, the causative agent of tuberculosis (TB). Previously …

Rationale Current tools available to study the molecular epidemiology of tuberculosis do not
provide information about the directionality and sequence of transmission for tuberculosis …

Contact tracing complemented with genotyping is considered an important means of
understanding person-to-person transmission of tuberculosis (TB). It still remains unclear …

Analyzing whole-genome sequencing data of Mycobacterium tuberculosis complex (MTBC)
isolates in a standardized workflow enables both comprehensive antibiotic resistance …

Background Nearly two decades after completion of the genome sequence of
Mycobacterium tuberculosis (MTB), and with the advent of next generation sequencing …

Whole-genome sequencing (WGS) allows for effective tracing of Mycobacterium
tuberculosis complex (MTBC)(tuberculosis pathogens) transmission. However, it is difficult to …