Background The etiopathophysiology of schizophrenia has long been linked to stress and
the influence of stress is important in all stages of the illness. Previous examinations of …

Current pathophysiological models of schizophrenia suggest that stress contributes to the
etiology and trajectory of the disorder. We investigated if allostatic load (AL), an integrative …

Background Stress plays an important role in the etiology of schizophrenia. However, the
mechanisms by which chronic physiological stress and perceived stress relate to the clinical …

Stress plays a significant role in schizophrenia from disease onset to exacerbation of
psychotic symptoms. Allostatic load (AL) is a measure of cumulative stress to the organism …

Stress exposure leads to the activation of several biological mechanisms that have been
termed allostasis. These processes enable adaptation to novel situations; however; their …

Adaptation to stress leads to the activation of several biological systems that maintain
homeostasis and enable effective coping with challenges. These adaptive processes have …

Reduced cortical gray matter integrity and cognitive abilities are among core deficits in
schizophrenia. We hypothesized that higher allostatic load (AL) that accounts for exposure …

Accumulating evidence indicates that stress plays an important role in the development of
psychotic disorders. Recent studies have revealed that patients with first-episode psychosis …

Although it is widely recognized that stress plays a key role in the pathophysiology of
schizophrenia, little is known regarding the particular types of stress patients experience …

Objective: In the vulnerability-stress concept of schizophrenia, schizophrenic patients are
thought to display increased sensitivity to stress. Little is known about the biological …