Background Stroke is a leading cause of mortality and disability worldwide and the
economic costs of treatment and post-stroke care are substantial. The Global Burden of …

Background Accurate diagnosis and early detection of complex diseases, such as
Parkinson's disease, has the potential to be of great benefit for researchers and clinical …

Background Parkinson's disease is heterogeneous in symptom presentation and
progression. Increased understanding of both aspects can enable better patient …

Importance Accurate and up-to-date estimates on incidence, prevalence, mortality, and
disability-adjusted life-years (burden) of neurological disorders are the backbone of …

WHO categorizes causes of death and disability into (1) communicable diseases, maternal
and perinatal conditions, and nutritional deficiencies;(2) non-communicable diseases …

Neurological disorders are the leading cause of disability and the second leading cause of
death worldwide. In the past 30 years, the absolute numbers of deaths and people with …

Up-to-date, accurate information on the disease burden of motor neuron disease (MND) is
the cornerstone for evidence-based resource allocation and healthcare planning. We aimed …

Parkinson disease (PD) is the second most common age-related neurodegenerative
condition diagnosed in North America. We recently demonstrated, using multiple …

Background Parkinson's disease is associated with an increased incidence of cognitive
impairment and dementia. Predicting who is at risk of cognitive decline early in the disease …

Background Better understanding and prediction of progression of Parkinson's disease
could improve disease management and clinical trial design. We aimed to use longitudinal …