Serum paraoxonase-1 levels are significantly decreased in the presence of insulin resistance

A Gateva, Y Assyov, A Tsakova… - Experimental and …, 2016 - thieme-connect.com
Paraoxonase-1 (PON1) is an extracellular esterase contributing to the anti-atherogenic and
anti-inflammatory properties of HDL and has a protective role in the progression of …

Implications of serum paraoxonase activity in obesity, diabetes mellitus, and dyslipidemia

SK Kota, LK Meher, SK Kota, S Jammula… - Indian journal of …, 2013 - journals.lww.com
Abstract Human serum paraoxonase 1 (PON1) is an enzyme with esterase activity, and is
physically bound to high-density lipoproteins (HDL). It plays a key role in the action of HDL …

Paraoxonase-1 is a better indicator than HDL of atherosclerosis–A pilot study in North Indian population

K Singh, R Singh, S Chandra, S Tyagi - Diabetes & Metabolic Syndrome …, 2018 - Elsevier
Objectives The present study aims to evaluate the levels of HDL and Paraoxonase-1 (PON1)
and their correlation in atherosclerotic patients with and without diabetic mellitus (DM) as …

Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome

KW Liang, WJ Lee, WL Lee, SY Lin, SL Hsu, CJ Wan… - Clinica Chimica …, 2011 - Elsevier
BACKGROUND: Paraoxonase-1 (PON1) is an esterase associated with the high-density
lipoprotein (HDL) in serum. To date, there have been few reports about circulating PON1 …

[PDF][PDF] Paraoxonase activity in type 2 diabetes mellitus patients with and without complications

R Suvarna, SS Rao, C Joshi, V Kedage… - Journal of clinical and …, 2011 - researchgate.net
Introduction: Type 2 diabetes mellitus (DM) is a disease of metabolic dysregulation. The
current study was undertaken to understand the relationship between the fasting lipid profile …

Paraoxonase 1 gene polymorphism relationship with type 2 diabetes mellitus

N Elattar, EE Swelam, E Hamed, A Elnahal, E Mostafa - Life Sci J, 2012 - hero.epa.gov
Background: Human serum paraoxonase1 (PON1) an antioxidant enzyme closely
associated with high density lipoprotein (HDL) has been implicated in the prevention of low …

Paraoxonase-1 activity in type 2 diabetes mellitus with and without nephropathy

NH El-said, MM Nasr-Allah, NA Sadik… - The egyptian journal of …, 2015 - Springer
Abstract Background Paraoxonase-1 (PON-1) is an enzyme synthesized in the liver that has
antioxidant functions as it binds to the HDL particles and prevents the oxidation of LDL …

A case‐control study: the association of serum paraoxonase 1 activity and concentration with the development of type 2 diabetes mellitus

JA Crow, EC Meek, RW Wills… - … Research and Reviews, 2018 - Wiley Online Library
Background A longitudinal study assessed serum paraoxonase 1 (PON1) activity and
concentration as affected by age and as associated with the development of type 2 diabetes …

Paraoxonase 1 (PON1) and its relationship to lipid variables, age and gender in healthy volunteers

K Sumegová, P Blažíček, B Fuhrman, I Waczulíková… - Biologia, 2006 - degruyter.com
Recent studies implied that low-density lipoprotein (LDL) modified predominantly by
oxidation or glycation, significantly contributes to the formation of atherosclerotic lesions. In …

Lower serum paraoxonase-1 activity is related to linoleic and docosahexanoic fatty acids in type 2 diabetic patients

Z Rasic-Milutinovic, T Popovic… - Archives of Medical …, 2012 - Elsevier
BACKGROUND: Serum paraoxonase-1 (PON-1) activity is decreased in clinical conditions
associated with low high-density lipoprotein cholesterol (HDL-C), increased lipid …