MR microscopy of formalin fixed paraffin embedded histology specimens

S Macura, PK Mishra, JD Gamez… - Magnetic resonance in …, 2014 - Wiley Online Library
Purpose Archived formalin‐fixed paraffin‐embedded (FFPE) tissue collections represent a
valuable informational resource for numerous studies. However, there is no NMR signal …

[HTML][HTML] Protocol for tissue processing and paraffin embedding of mouse brains following ex vivo MRI

A Smart, C Tisca, IN Huszar, D Kor, O Ansorge… - STAR protocols, 2023 - Elsevier
Combining histology and ex vivo MRI from the same mouse brain is a powerful way to study
brain microstructure. Mouse brains prepared for ex vivo MRI are often kept in storage …

Optimization of sample preparation for MRI of formaldehyde-fixed brains

Y Leprince, B Schmitt, É Chaillou… - 23rd annual meeting …, 2015 - cea.hal.science
Magnetic resonance imaging of post-mortem brains allows long acquisition times up to
several days and can be used to obtain high-resolution images at high field (7 T) which can …

[HTML][HTML] A Method to Image Brain Tissue Frozen at Autopsy

G Nair, R Sun, H Merkle, Q Xu, K Hoskin, K Bree… - NeuroImage, 2024 - Elsevier
Abstract Magnetic Resonance Imaging (MRI) can provide the location and signal
characteristics of pathological regions within a postmortem tissue block, thereby improving …

Comparison of ethanol versus formalin fixation on preservation of histology and RNA in laser capture microdissected brain tissues

JMF Su, L Perlaky, XN Li, HCE Leung… - Brain …, 2004 - Wiley Online Library
Although RNA can be retrieved from formalin‐fixed, paraffin‐embedded (FFPE) tissues, the
yield is low, and the RNA is fragmented. Recent advances in gene expression profiling …

Quantitative intact specimen magnetic resonance microscopy at 3.0 T

KG Bath, HU Voss, D Jing, S Anderson… - Magnetic resonance …, 2009 - Elsevier
In this report, we discuss the application of a methodology for high-contrast, high-resolution
magnetic resonance microscopy (MRM) of murine tissue using a 3.0-T imaging system. We …

The choice of embedding media affects image quality, tissue R2*, and susceptibility behaviors in post‐mortem brain MR microscopy at 7.0T

P Dusek, VI Madai, T Huelnhagen… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose The quality and precision of post‐mortem MRI microscopy may vary depending on
the embedding medium used. To investigate this, our study evaluated the impact of 5 widely …

Metabolic support of excised, living brain tissues during magnetic resonance microscopy acquisition

JJ Flint, K Menon, B Hansen, J Forder… - JoVE (Journal of …, 2017 - jove.com
This protocol describes the procedures necessary to support normal metabolic functions of
acute brain slice preparations during the collection of magnetic resonance (MR) microscopy …

Target-specific contrast agents for magnetic resonance microscopy

ML Blackwell, CT Farrar, B Fischl, BR Rosen - Neuroimage, 2009 - Elsevier
High-resolution ex vivo magnetic resonance (MR) imaging can be used to delineate
prominent architectonic features in the human brain, but increased contrast is required to …

[PDF][PDF] Effect of embedding media on post-mortem MRI of formalin-fixed brain tissue at 7.0 T

P Dusek, VI Madai, M Dieringer, F Hezel… - Proc Intl Soc Mag …, 2014 - researchgate.net
Background Methods Results Conclusions Page 1 Effect of embedding media on post-mortem
MRI of formalin-fixed brain tissue at 7.0 T Petr Dusek 1,2 , Vince Istvan Madai 3 , Matthias …