For the interpretation of magnetic resonance imaging (MRI) abnormalities in brain
pathology, often ex vivo tissue is used. The purpose of this study was to determine the …

Purpose Formalin fixation prevents tissue autolysis by crosslinking proteins and changes
tissue microstructure and MRI signal characteristics. Previous studies showed high …

Purpose: MR imaging of post mortem brains has the potential to yield volumetric information
and define the extent of structural changes prior to pathological examination. Although …

Post‐mortem MRI of the brain is increasingly applied in neuroscience for a better
understanding of the contrast mechanisms of disease induced tissue changes. However, the …

Purpose Postmortem MRI can be used to reveal important pathologies and establish
radiology–pathology correlations. However, quantitative MRI values are altered by tissue …

Magnetic resonance imaging of post-mortem brains allows long acquisition times up to
several days and can be used to obtain high-resolution images at high field (7 T) which can …

Unlike in vivo imaging, postmortem MRI allows for invasive examination of the tissue
specimen immediately after the MR scan. However, natural tissue decomposition and …

Purpose To investigate changes in magnetic resonance imaging (MRI) indices following
formalin fixation of postmortem multiple sclerosis (MS) cortical gray matter (CGM) …

Purpose The purpose of this investigation was to compare magnetization-prepared rapid
gradient echo (MP-RAGE) images with T1-weighted images (T1WI) and T2-weighted …

Purpose The quality and precision of post‐mortem MRI microscopy may vary depending on
the embedding medium used. To investigate this, our study evaluated the impact of 5 widely …