Whole-genome sequencing to detect recent transmission of Mycobacterium tuberculosis in settings with a high burden of tuberculosis

T Luo, C Yang, Y Peng, L Lu, G Sun, J Wu, X Jin… - Tuberculosis, 2014 - Elsevier
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been used to trace
the transmission of M. tuberculosis, the causative agent of tuberculosis (TB). Previously …

Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission

KN Nelson, S Talarico, S Poonja… - Frontiers in Public …, 2022 - frontiersin.org
Tuberculosis (TB) control programs use whole-genome sequencing (WGS) of
Mycobacterium tuberculosis (Mtb) for detecting and investigating TB case clusters. Existence …

[HTML][HTML] Whole-genome sequencing for rapid, reliable and routine investigation of Mycobacterium tuberculosis transmission in local communities

F Zakham, S Laurent, ALE Carreira, A Corbaz… - New microbes and new …, 2019 - Elsevier
Contact investigations following the diagnosis of active tuberculosis (TB) are paramount for
the control of the disease. Epidemiological data are very powerful for contact tracing but …

[HTML][HTML] Role and value of whole genome sequencing in studying tuberculosis transmission

V Nikolayevskyy, S Niemann, R Anthony… - Clinical Microbiology …, 2019 - Elsevier
Background Tuberculosis (TB) remains a serious public health threat worldwide.
Theoretically ultimate resolution of whole genome sequencing (WGS) for Mycobacterium …

Marked Microevolution of a Unique Mycobacterium tuberculosis Strain in 17 Years of Ongoing Transmission in a High Risk Population

C Mehaffy, JL Guthrie, DC Alexander, R Stuart, E Rea… - Plos one, 2014 - journals.plos.org
The transmission and persistence of Mycobacterium tuberculosis within high risk
populations is a threat to tuberculosis (TB) control. In the current study, we used whole …

Whole Genome Sequencing versus Traditional Genotyping for Investigation of a Mycobacterium tuberculosis Outbreak: A Longitudinal Molecular Epidemiological …

A Roetzer, R Diel, TA Kohl, C Rückert, U Nübel… - PLoS …, 2013 - journals.plos.org
Background Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to
guide efficient tuberculosis control strategies. Traditional strain typing lacks sufficient …

Genomic epidemiology of Lineage 4 Mycobacterium tuberculosis subpopulations in New York City and New Jersey, 1999–2009

TS Brown, A Narechania, JR Walker, PJ Planet… - BMC genomics, 2016 - Springer
Background Whole genome sequencing (WGS) has rapidly become an important research
tool in tuberculosis epidemiology and is likely to replace many existing methods in public …

Tracking a tuberculosis outbreak over 21 years: strain-specific single-nucleotide polymorphism typing combined with targeted whole-genome sequencing

D Stucki, M Ballif, T Bodmer, M Coscolla… - The Journal of …, 2015 - academic.oup.com
Background. Whole-genome sequencing (WGS) is increasingly used in molecular-
epidemiological investigations of bacterial pathogens, despite cost-and time-intensive …

Whole genome sequencing of Mycobacterium tuberculosis for detection of recent transmission and tracing outbreaks: a systematic review

V Nikolayevskyy, K Kranzer, S Niemann, F Drobniewski - Tuberculosis, 2016 - Elsevier
Contact tracing complemented with genotyping is considered an important means of
understanding person-to-person transmission of tuberculosis (TB). It still remains unclear …

Within-host Mycobacterium tuberculosis diversity and its utility for inferences of transmission

MA Martin, RS Lee, LA Cowley… - Microbial …, 2018 - microbiologyresearch.org
Whole genome sequencing in conjunction with traditional epidemiology has been used to
reconstruct transmission networks of Mycobacterium tuberculosis during outbreaks. Given its …