Methods for estimating confidence intervals in interrupted time series analyses of health interventions

F Zhang, AK Wagner, SB Soumerai… - Journal of clinical …, 2009 - Elsevier
OBJECTIVE: Interrupted time series (ITS) is a strong quasi-experimental research design,
which is increasingly applied to estimate the effects of health services and policy …

[HTML][HTML] Comparison of six statistical methods for interrupted time series studies: empirical evaluation of 190 published series

SL Turner, A Karahalios, AB Forbes, M Taljaard… - BMC Medical Research …, 2021 - Springer
Abstract Background The Interrupted Time Series (ITS) is a quasi-experimental design
commonly used in public health to evaluate the impact of interventions or exposures …

Testing the validity of the single interrupted time series design

K Baicker, T Svoronos - 2019 - nber.org
Given the complex relationships between patients' demographics, underlying health needs,
and outcomes, establishing the causal effects of health policy and delivery interventions on …

Challenges to validity in single‐group interrupted time series analysis

A Linden - Journal of evaluation in clinical practice, 2017 - Wiley Online Library
Rationale, aims and objectives Single‐group interrupted time series analysis (ITSA) is a
popular evaluation methodology in which a single unit of observation is studied; the …

Reflection on modern methods: a common error in the segmented regression parameterization of interrupted time-series analyses

H Xiao, O Augusto, BH Wagenaar - International journal of …, 2021 - academic.oup.com
Interrupted time-series (ITS) designs are a robust and increasingly popular non-randomized
study design for strong causal inference in the evaluation of public health interventions. One …

Difference in difference, controlled interrupted time series and synthetic controls

J Lopez Bernal, S Cummins… - International journal of …, 2019 - academic.oup.com
We thank Benmarhnia and Rudolph 1 for their critical appraisal of our recent article on the
use of controls in interrupted time series (ITS) studies. 2 This offers the opportunity to clarify …

Regression based quasi-experimental approach when randomisation is not an option: interrupted time series analysis

E Kontopantelis, T Doran, DA Springate, I Buchan… - bmj, 2015 - bmj.com
Regression based quasi-experimental approach when randomisation is not an option:
interrupted time series analysis Page 1 ReseaRch Methods & RepoRtinG 1 OPEN ACCESS …

[HTML][HTML] A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation

A Fretheim, F Zhang, D Ross-Degnan… - Journal of clinical …, 2015 - Elsevier
Objectives There is often substantial uncertainty about the impacts of health system and
policy interventions. Despite that, randomized controlled trials (RCTs) are uncommon in this …

Methods, applications and challenges in the analysis of interrupted time series data: a scoping review

JE Ewusie, C Soobiah, E Blondal… - Journal of …, 2020 - Taylor & Francis
Objective Interrupted time series (ITS) designs are robust quasi-experimental designs
commonly used to evaluate the impact of interventions and programs implemented in …

Segmented regression analysis of interrupted time series studies in medication use research

AK Wagner, SB Soumerai, F Zhang… - Journal of clinical …, 2002 - Wiley Online Library
Interrupted time series design is the strongest, quasi‐experimental approach for evaluating
longitudinal effects of interventions. Segmented regression analysis is a powerful statistical …