Design characteristics and statistical methods used in interrupted time series studies evaluating public health interventions: a review

SL Turner, A Karahalios, AB Forbes, M Taljaard… - Journal of Clinical …, 2020 - Elsevier
Objectives Interrupted time series (ITS) designs are frequently used in public health to
examine whether an intervention or exposure has influenced health outcomes. Few reviews …

[HTML][HTML] Comparison of six statistical methods for interrupted time series studies: empirical evaluation of 190 published series

SL Turner, A Karahalios, AB Forbes, M Taljaard… - BMC Medical Research …, 2021 - Springer
Abstract Background The Interrupted Time Series (ITS) is a quasi-experimental design
commonly used in public health to evaluate the impact of interventions or exposures …

Simulation-based power calculation for designing interrupted time series analyses of health policy interventions

F Zhang, AK Wagner, D Ross-Degnan - Journal of clinical epidemiology, 2011 - Elsevier
OBJECTIVE: Interrupted time series is a strong quasi-experimental research design to
evaluate the impacts of health policy interventions. Using simulation methods, we estimated …

[HTML][HTML] Evaluation of statistical methods used in the analysis of interrupted time series studies: a simulation study

SL Turner, AB Forbes, A Karahalios, M Taljaard… - BMC medical research …, 2021 - Springer
Background Interrupted time series (ITS) studies are frequently used to evaluate the effects
of population-level interventions or exposures. However, examination of the performance of …

Methods for estimating confidence intervals in interrupted time series analyses of health interventions

F Zhang, AK Wagner, SB Soumerai… - Journal of clinical …, 2009 - Elsevier
OBJECTIVE: Interrupted time series (ITS) is a strong quasi-experimental research design,
which is increasingly applied to estimate the effects of health services and policy …

Methods, applications and challenges in the analysis of interrupted time series data: a scoping review

JE Ewusie, C Soobiah, E Blondal… - Journal of …, 2020 - Taylor & Francis
Objective Interrupted time series (ITS) designs are robust quasi-experimental designs
commonly used to evaluate the impact of interventions and programs implemented in …

The use of controls in interrupted time series studies of public health interventions

J Lopez Bernal, S Cummins… - International journal of …, 2018 - academic.oup.com
Interrupted time series analysis differs from most other intervention study designs in that it
involves a before-after comparison within a single population, rather than a comparison with …

Design characteristics and statistical methods used in interrupted time series studies evaluating public health interventions: protocol for a review

SL Turner, A Karahalios, AB Forbes, M Taljaard… - BMJ open, 2019 - bmjopen.bmj.com
Introduction An interrupted time series (ITS) design is an important observational design
used to examine the effects of an intervention or exposure. This design has particular utility …

A methodological framework for model selection in interrupted time series studies

JL Bernal, S Soumerai, A Gasparrini - Journal of clinical epidemiology, 2018 - Elsevier
Interrupted time series (ITS) is a powerful and increasingly popular design for evaluating
public health and health service interventions. The design involves analyzing trends in the …

[HTML][HTML] Methodology and reporting characteristics of studies using interrupted time series design in healthcare

J Hudson, S Fielding, CR Ramsay - BMC medical research methodology, 2019 - Springer
Abstract Background Randomised controlled trials (RCTs) are considered the gold standard
when evaluating the causal effects of healthcare interventions. When RCTs cannot be used …