Obesity mechanism after hypothalamic damage: Cohort analysis of neuroimaging, psychological, cognitive, and clinical phenotyping data
Objective The hypothalamus regulates energy homeostasis, and its damage results in
severe obesity. We aimed to investigate the multifaceted characteristics of hypothalamic …
severe obesity. We aimed to investigate the multifaceted characteristics of hypothalamic …
Semiquantitative analysis of hypothalamic damage on MRI predicts risk for hypothalamic obesity
Objective Excessive weight gain frequently occurs in patients with hypothalamic tumors and
lesions leading to hypothalamic obesity (HO). Methods Digital brain magnetic resonance …
lesions leading to hypothalamic obesity (HO). Methods Digital brain magnetic resonance …
Hypothalamic damage is associated with inflammatory markers and worse cognitive performance in obese subjects
J Puig, G Blasco, J Daunis-i-Estadella… - The Journal of …, 2015 - academic.oup.com
Context: Growing evidence implicates hypothalamic inflammation in the pathogenesis of diet-
induced obesity and cognitive dysfunction in rodent models. Few studies have addressed …
induced obesity and cognitive dysfunction in rodent models. Few studies have addressed …
Low‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity
Objective The main objective of this study is to better understand the effects of diet‐induced
weight loss on brain connectivity in response to changes in glucose levels in individuals with …
weight loss on brain connectivity in response to changes in glucose levels in individuals with …
Hypothalamic dysfunction in obesity and metabolic disorders
S Carmo-Silva, C Cavadas - Obesity and brain function, 2017 - Springer
The hypothalamus is the brain region responsible for the maintenance of energetic
homeostasis. The regulation of this process arises from the ability of the hypothalamus to …
homeostasis. The regulation of this process arises from the ability of the hypothalamus to …
[HTML][HTML] Neural structural abnormalities behind altered brain activation in obesity: Evidence from meta-analyses of brain activation and morphometric data
Obesity represents a risk factor for disability with a major bearing on life expectancy.
Neuroimaging techniques are contributing to clarify its neurobiological underpinnings. Here …
Neuroimaging techniques are contributing to clarify its neurobiological underpinnings. Here …
Hypothalamic neurogenesis and its implications for obesity-induced anxiety disorders
E Samodien, N Chellan - Frontiers in Neuroendocrinology, 2021 - Elsevier
Obesity and anxiety are public health problems that have no effective cure. Obesity-induced
anxiety is also the most common behavioural trait exhibited amongst obese patients, with …
anxiety is also the most common behavioural trait exhibited amongst obese patients, with …
Hypothalamic obesity: prevalence, associations and longitudinal trends in weight in a specialist adult neuroendocrine clinic
CA Steele, DJ Cuthbertson… - European journal of …, 2013 - academic.oup.com
Objective Obesity is highly prevalent among adults with acquired, structural hypothalamic
damage. We aimed to determine hormonal and neuroanatomical variables associated with …
damage. We aimed to determine hormonal and neuroanatomical variables associated with …
Cognitive function and decline in obesity
KS Sellbom, J Gunstad - Journal of Alzheimer's Disease, 2012 - content.iospress.com
Obesity is a significant contemporary health concern that carries wide-ranging implications
for society, as well as for individual health and well-being. In particular, the …
for society, as well as for individual health and well-being. In particular, the …
Mental function and obesity
N Yamada-Goto, G Katsuura… - Functional Brain Mapping …, 2013 - books.google.com
Obesity is defined as a high body mass index (BMI) with a large amount of adiposity. A
chronic excess energy intake above energy expenditure leads to abnormal or excessive fat …
chronic excess energy intake above energy expenditure leads to abnormal or excessive fat …
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