Hypothalamic subregion alterations in anorexia nervosa and obesity: Association with appetite‐regulating hormone levels
H Alzaid, JJ Simon, G Brugnara… - … Journal of Eating …, 2024 - Wiley Online Library
Objective Anorexia nervosa (AN) and obesity are weight‐related disorders with imbalances
in energy homeostasis that may be due to hormonal dysregulation. Given the importance of …
in energy homeostasis that may be due to hormonal dysregulation. Given the importance of …
Hypothalamic inflammation: is there evidence for human obesity?
RB Kumar, LJ Aronne - Current obesity reports, 2014 - Springer
With increasing awareness of the obesity epidemic have come research efforts to
understand the pathophysiology of body weight and appetite regulation. Clinical trials of diet …
understand the pathophysiology of body weight and appetite regulation. Clinical trials of diet …
Functional neuroimaging in craniopharyngioma: a useful tool to better understand hypothalamic obesity?
CL Roth, E Aylward, O Liang, NM Kleinhans, G Pauley… - Obesity facts, 2012 - karger.com
Objective: To use functional magnetic resonance imaging (fMRI) in craniopharyngioma (CP)
patients to examine the hypothesis that hypothalamic damage due to CP and its treatment …
patients to examine the hypothesis that hypothalamic damage due to CP and its treatment …
Obesity is associated with hypothalamic injury in rodents and humans
Rodent models of obesity induced by consuming high-fat diet (HFD) are characterized by
inflammation both in peripheral tissues and in hypothalamic areas critical for energy …
inflammation both in peripheral tissues and in hypothalamic areas critical for energy …
The role of corticostriatal–hypothalamic neural circuits in feeding behaviour: implications for obesity
RE Clarke, A Verdejo‐Garcia… - Journal of …, 2018 - Wiley Online Library
Emerging evidence from human imaging studies suggests that obese individuals have
altered connectivity between the hypothalamus, the key brain region controlling energy …
altered connectivity between the hypothalamus, the key brain region controlling energy …
Loss of pons-to-hypothalamic white matter tracks in brainstem obesity
JQ Purnell, DL Lahna, MH Samuels… - International journal of …, 2014 - nature.com
Hyperphagia and obesity have been reported following damage to the hypothalamus in
humans. Other brain sites are also postulated to be involved in the control of food intake and …
humans. Other brain sites are also postulated to be involved in the control of food intake and …
The central nervous system control of energy homeostasis: High fat diet induced hypothalamic microinflammation and obesity
L Yan, J Li - Brain research bulletin, 2022 - Elsevier
Obesity is believed to arise through the imbalance of energy homeostasis controlled by the
central nervous system, where the hypothalamus plays the fundamental role in energy …
central nervous system, where the hypothalamus plays the fundamental role in energy …
The neuropathology of obesity: insights from human disease
EB Lee, MP Mattson - Acta neuropathologica, 2014 - Springer
Obesity, a pathologic state defined by excess adipose tissue, is a significant public health
problem as it affects a large proportion of individuals and is linked with increased risk for …
problem as it affects a large proportion of individuals and is linked with increased risk for …
Brain structural and functional alterations in individuals with combined overweight/obesity and mood disorders: A systematic review of neuroimaging studies
X Zhang, L Han, C Lu, RS McIntyre, KM Teopiz… - Journal of Affective …, 2023 - Elsevier
Growing evidence suggests there is a bidirectional relationship between depression and
obesity, which are associated with structural and functional brain abnormalities. However …
obesity, which are associated with structural and functional brain abnormalities. However …
Neuroimaging and neuroendocrine insights into food cravings and appetite interventions in obesity
This article reviews the previous studies on the distinction between food cravings and
appetite, and how they are regulated by hormones and reflected in brain activity. Based on …
appetite, and how they are regulated by hormones and reflected in brain activity. Based on …