Background. Whole-genome sequencing (WGS) is increasingly used in molecular-
epidemiological investigations of bacterial pathogens, despite cost-and time-intensive …

Background Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to
guide efficient tuberculosis control strategies. Traditional strain typing lacks sufficient …

Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been used to trace
the transmission of M. tuberculosis, the causative agent of tuberculosis (TB). Previously …

Contact investigations following the diagnosis of active tuberculosis (TB) are paramount for
the control of the disease. Epidemiological data are very powerful for contact tracing but …

Whole-genome sequencing (WGS) allows for effective tracing of Mycobacterium
tuberculosis complex (MTBC)(tuberculosis pathogens) transmission. However, it is difficult to …

Whole genome sequencing in conjunction with traditional epidemiology has been used to
reconstruct transmission networks of Mycobacterium tuberculosis during outbreaks. Given its …

Background Tuberculosis incidence in the UK has risen in the past decade. Disease control
depends on epidemiological data, which can be difficult to obtain. Whole-genome …

Since 1992, Denmark has documented the largest outbreak of tuberculosis in Scandinavia
ascribed to a single genotype, termed C2/1112–15. As of spring 2017, the International …

The control of tuberculosis depends on the identification and treatment of infectious patients
and their contacts, who are currently identified through a combined approach of genotyping …

Controlling human-to-human tuberculosis (TB) transmission is key for achieving the targets
of the End TB Strategy set by the World Health Organization (WHO)[1, 2]. Stopping TB …