Contact tracing complemented with genotyping is considered an important means of
understanding person-to-person transmission of tuberculosis (TB). It still remains unclear …

Background Tuberculosis (TB) remains a serious public health threat worldwide.
Theoretically ultimate resolution of whole genome sequencing (WGS) for Mycobacterium …

The control of tuberculosis depends on the identification and treatment of infectious patients
and their contacts, who are currently identified through a combined approach of genotyping …

Background Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to
guide efficient tuberculosis control strategies. Traditional strain typing lacks sufficient …

Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been used to trace
the transmission of M. tuberculosis, the causative agent of tuberculosis (TB). Previously …

Background Whole genome sequencing (WGS) is becoming an important part of
epidemiological investigations of infectious diseases due to greater resolution and cost …

Background Mycobacterium tuberculosis is characterised by limited genomic diversity,
which makes the application of whole genome sequencing particularly attractive for clinical …

Whole genome sequencing (WGS) can help to relate Mycobacterium tuberculosis genomes
to one another to assess genetic relatedness and infer the likelihood of transmission …

Whole-genome sequencing (WGS) is now common as a result of new technologies that can
rapidly sequence a complete bacterial genome for US $500 or less. Many studies have …

Background Tuberculosis incidence in the UK has risen in the past decade. Disease control
depends on epidemiological data, which can be difficult to obtain. Whole-genome …