Abstract Background Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem
Repeat (MIRU-VNTR) typing is widely used in high-income countries to determine …

To improve understanding of the factors influencing tuberculosis transmission and the role of
pathogen variation, we sequenced all available specimens from patients diagnosed over 15 …

Background Whole genome sequencing provides better delineation of transmission clusters
in Mycobacterium tuberculosis than traditional methods. However, its ability to reveal …

Background Genotyping of Mycobacterium tuberculosis isolates is a powerful tool for
epidemiological control of tuberculosis (TB) and phylogenetic exploration of the pathogen …

We used whole-genome sequencing (WGS) to delineate transmission networks and
investigate the benefits of WGS during cluster investigation. We included clustered cases of …

Background Whole genome sequencing (WGS) is a reliable tool for studying tuberculosis
(TB) transmission. WGS data are usually processed by custom-built analysis pipelines with …

Standardized mycobacterial interspersed repetitive-unit-variable-number tandem repeat
(MIRU-VNTR) typing based on 15 and 24 loci recently has been proposed for …

Background An outbreak of tuberculosis occurred over a 3-year period in a medium-size
community in British Columbia, Canada. The results of mycobacterial interspersed repetitive …

To determine the proportion of reported tuberculosis (TB) cases due to recent transmission
in the United States, we conducted a cross-sectional study to examine culture-positive TB …

Background. Recurrent tuberculosis is a major health burden and may be due to relapse
with the original strain or reinfection with a new strain. Methods. In a population-based study …