Rationale Current tools available to study the molecular epidemiology of tuberculosis do not
provide information about the directionality and sequence of transmission for tuberculosis …

In a study of 302 Mycobacterium tuberculosis clinical isolates from the low-incidence
Canadian-born population of Quebec, we characterized a large endemic strain family by …

Standardized mycobacterial interspersed repetitive-unit-variable-number tandem repeat
(MIRU-VNTR) typing based on 15 and 24 loci recently has been proposed for …

Background Patients with Mycobacterium tuberculosis isolates sharing identical DNA
fingerprint patterns can be epidemiologically linked. However, municipal health services in …

This paper formulates a set of rules to classify genotypes of the Mycobacterium tuberculosis
complex (MTBC) into major lineages using spoligotypes and MIRU-VNTR results. The rules …

An optimized set of 24 mycobacterial interspersed repetitive-unit-variable-number tandem-
repeat (MIRU-VNTR) loci, including a discriminatory subset of 15 loci, has recently been …

Abstract Background Although Ethiopia ranks seventh among the world's 22 high-burden
tuberculosis (TB) countries, little is known about strain diversity and transmission. In this …

Background Understanding regional molecular epidemiology allows for the development of
more efficient tuberculosis prevention strategies in low-incidence settings. Methods We …

ABSTRACT IS 6110 restriction fragment length polymorphism (RFLP) genotyping is the most
widely used genotyping method to study the epidemiology of Mycobacterium tuberculosis …

Background Tuberculosis incidence in the UK has risen in the past decade. Disease control
depends on epidemiological data, which can be difficult to obtain. Whole-genome …