Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study

TM Walker, CLC Ip, RH Harrell, JT Evans… - The Lancet infectious …, 2013 - thelancet.com
Background Tuberculosis incidence in the UK has risen in the past decade. Disease control
depends on epidemiological data, which can be difficult to obtain. Whole-genome …

Whole-genome-based Mycobacterium tuberculosis surveillance: a standardized, portable, and expandable approach

TA Kohl, R Diel, D Harmsen, J Rothgänger… - Journal of clinical …, 2014 - Am Soc Microbiol
Whole-genome sequencing (WGS) allows for effective tracing of Mycobacterium
tuberculosis complex (MTBC)(tuberculosis pathogens) transmission. However, it is difficult to …

[HTML][HTML] Role and value of whole genome sequencing in studying tuberculosis transmission

V Nikolayevskyy, S Niemann, R Anthony… - Clinical Microbiology …, 2019 - Elsevier
Background Tuberculosis (TB) remains a serious public health threat worldwide.
Theoretically ultimate resolution of whole genome sequencing (WGS) for Mycobacterium …

Prospective universal application of mycobacterial interspersed repetitive-unit-variable-number tandem-repeat genotyping to characterize Mycobacterium tuberculosis …

N Alonso-Rodriguez, M Martínez-Lirola… - Journal of Clinical …, 2009 - Am Soc Microbiol
The use of molecular tools for genotyping Mycobacterium tuberculosis isolates in
epidemiological surveys in order to identify clustered and orphan strains requires faster …

Whole genome sequencing identifies bacterial factors affecting transmission of multidrug-resistant tuberculosis in a high-prevalence setting

A Dixit, L Freschi, R Vargas, R Calderon… - Scientific Reports, 2019 - nature.com
Whole genome sequencing (WGS) can elucidate Mycobacterium tuberculosis (Mtb)
transmission patterns but more data is needed to guide its use in high-burden settings. In a …

Comparison between RFLP and MIRU-VNTR Genotyping of Mycobacterium tuberculosis Strains Isolated in Stockholm 2009 to 2011

J Jonsson, S Hoffner, I Berggren, J Bruchfeld… - Plos one, 2014 - journals.plos.org
Our aim was to analyze the difference between methods for genotyping of Mycobacterium
tuberculosis complex isolates. We collected genotyping results from Restriction Fragment …

The Importance of Recent Infection with Mycobacterium tuberculosis in an Area with High HIV Prevalence: A Long-Term Molecular Epidemiological Study in Northern …

JR Glynn, AC Crampin, MD Yates… - The Journal of …, 2005 - academic.oup.com
Background The proportion of cases of tuberculosis due to recent infection can be estimated
in long-term population-based studies using molecular techniques. Here, we present what …

Whole Genome Sequencing Analysis of Intrapatient Microevolution in Mycobacterium tuberculosis: Potential Impact on the Inference of Tuberculosis Transmission

L Pérez-Lago, I Comas, Y Navarro… - The Journal of …, 2014 - academic.oup.com
Background. It has been accepted that the infection by Mycobacterium tuberculosis (M.
tuberculosis) can be more heterogeneous than considered. The emergence of clonal …

Clustered tuberculosis in a low-burden country: nationwide genotyping through 15 years

Z Kamper-Jørgensen, AB Andersen… - Journal of clinical …, 2012 - Am Soc Microbiol
Molecular genotyping of Mycobacterium tuberculosis has proved to be a powerful tool in
tuberculosis surveillance, epidemiology, and control. Based on results obtained through 15 …

Evaluation of the new advanced 15-loci MIRU-VNTR genotyping tool in Mycobacterium tuberculosis molecular epidemiology studies

N Alonso-Rodríguez, M Martínez-Lirola, M Herránz… - BMC microbiology, 2008 - Springer
Background During the last few years, PCR-based methods have been developed to
simplify and reduce the time required for genotyping Mycobacterium tuberculosis (MTB) by …