Over history, diseases have appeared and disappeared, or have increased or decreased in
frequency. These epidemiological trends have occurred more dramatically for infectious …

Since 2006, several longitudinal studies have assessed environmental or behavioural
factors that seem to modify the risk of developing Parkinson's disease. Increased risk of …

Background Neurological disorders are now the leading source of disability globally, and
ageing is increasing the burden of neurodegenerative disorders, including Parkinson's …

The causes of Parkinson's disease (PD), the second most common neurodegenerative
disorder, are still largely unknown. Current thinking is that major gene mutations cause only …

Neuromodulatory or even neuroprotective therapy could soon be available for Parkinson's
disease (PD), raising the question of how we should define and measure disease …

Parkinson's disease is a neurological disorder with evolving layers of complexity. It has long
been characterised by the classical motor features of parkinsonism associated with Lewy …

The clinical diagnosis of Parkinson's disease rests on the identification of the characteristics
related to dopamine deficiency that are a consequence of degeneration of the substantia …

Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical
presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; …

Summary 1· 8 billion people of diverse ethnicities and cultures live in the Western Pacific
Region. The increasing longevity of populations in this region is a major contributor to the …

Recent findings question our present understanding of Parkinson's disease and suggest that
new research criteria for the diagnosis of Parkinson's disease are needed, similar to those …