The pulmonary route of administration is used for both locally and systemically acting drugs.
However, knowledge gaps about the fate of aerosol particles after deposition in the lung …

In vitro dissolution testing is routinely used in the development of pharmaceutical products.
Whilst the dissolution testing methods are well established and standardized for oral dosage …

The purpose of this article is to review the suitability of the analytical and statistical
techniques that have thus far been developed to assess the dissolution behavior of particles …

To overcome some of the shortfalls of the types of dissolution testing currently used for
pulmonary products, a new custom-built dissolution apparatus has been developed. For …

Purpose To evaluate different dissolution testing methods and subsequently develop a
simple to perform but reproducible and discriminating dissolution technique for inhalative …

The composition, morphology and dissolution profile of particles and micro-sized
agglomerates delivered upon inhalation may have a significant impact on the product …

Dissolution testing is routinely used for quality control purposes to test batch‐to‐batch
consistency, stability and detect manufacturing deviations of pharmaceutical products. While …

Inhalation is the preferred route for the treatment of lung diseases. More recently, also
formulations for systemic treatment have been developed. For efficient development of …

The aim of this study was the development and evaluation of a miniaturized setup for in vitro
dissolution testing of inhalation powders based on an adapted Transwell system with …

Dry powder inhalation therapy has been effective in treating localized lung diseases such
asthma, chronic obstructive pulmonary diseases (COPD), cystic fibrosis and lung infections …