[HTML][HTML] Influence of particle diameter on aerosolization performance and release of budesonide loaded mesoporous silica particles
The potential of micron-sized amorphous mesoporous silica particles as a novel controlled
release drug delivery system for pulmonary administration has been investigated …
release drug delivery system for pulmonary administration has been investigated …
Aerosol droplet delivery of mesoporous silica nanoparticles: A strategy for respiratory-based therapeutics
A highly versatile nanoplatform that couples mesoporous silica nanoparticles (MSNs) with
an aerosol technology to achieve direct nanoscale delivery to the respiratory tract is …
an aerosol technology to achieve direct nanoscale delivery to the respiratory tract is …
Excipient-free nanoporous microparticles of budesonide for pulmonary delivery
The aim of this study was to investigate the application of a spray-drying process for the
production of nanoporous microparticles (NPMPs) to budesonide, and to characterise the …
production of nanoporous microparticles (NPMPs) to budesonide, and to characterise the …
Feasibility study of mesoporous silica particles for pulmonary drug delivery: Therapeutic treatment with dexamethasone in a mouse model of airway inflammation
T Gulin-Sarfraz, S Jonasson, E Wigenstam… - Pharmaceutics, 2019 - mdpi.com
Diseases in the respiratory tract rank among the leading causes of death in the world, and
thus novel and optimized treatments are needed. The lungs offer a large surface for drug …
thus novel and optimized treatments are needed. The lungs offer a large surface for drug …
[HTML][HTML] Inhalable porous particles as dual micro-nano carriers demonstrating efficient lung drug delivery for treatment of tuberculosis
JEC Pacheco, T Yalovenko, A Riaz, N Kotov… - Journal of Controlled …, 2024 - Elsevier
Inhalation therapy treating severe infectious disease is among the more complex and
emerging topics in controlled drug release. Micron-sized carriers are needed to deposit …
emerging topics in controlled drug release. Micron-sized carriers are needed to deposit …
[HTML][HTML] Preparation and in-vitro evaluation of rifampin-loaded mesoporous silica nanoaggregates by an experimental design
M Mohseni, K Gilani, Z Bahrami… - Iranian Journal of …, 2015 - ncbi.nlm.nih.gov
The goal of this research is preparation, optimization and in-vitro evaluation of rifampin-
loaded silica nanoparticles in order to use in the pulmonary drug delivery. Nanoparticles are …
loaded silica nanoparticles in order to use in the pulmonary drug delivery. Nanoparticles are …
Impact of surfactant selection on the formulation and characterization of microparticles for pulmonary drug delivery
E Cocks, O Alpar, S Somavarapu… - Drug Development and …, 2015 - Taylor & Francis
The effect of suspension stabilizers, internal aqueous phase volume and polymer amount
were investigated for the production of protein loaded poly (d, l lactide-co-glycolide)(PLGA) …
were investigated for the production of protein loaded poly (d, l lactide-co-glycolide)(PLGA) …
Inhalable microspheres with hierarchical pore size for tuning the release of biotherapeutics in lungs
A series of customized inhalable mono-dispersed poly-L-lactide microspheres (PLA-MS)
having hierarchical pore structures with either open or closed porosity were synthesized by …
having hierarchical pore structures with either open or closed porosity were synthesized by …
Formulation and physical characterization of large porous particles for inhalation
R Vanbever, JD Mintzes, J Wang, J Nice, D Chen… - Pharmaceutical …, 1999 - Springer
Abstract Purpose. Relatively large (> 5 µm) and porous (mass density< 0.4 g/cm 3) particles
present advantages for the delivery of drugs to the lungs, eg, excellent aerosolization …
present advantages for the delivery of drugs to the lungs, eg, excellent aerosolization …
Solid lipid budesonide microparticles for controlled release inhalation therapy
A solid lipid microparticle system containing budesonide was prepared by oil in water
emulsification followed by spray drying. The solid lipid system was studied in terms of …
emulsification followed by spray drying. The solid lipid system was studied in terms of …