Interest of cyclodextrins in spray-dried microparticles formulation for sustained pulmonary delivery of budesonide
G Dufour, W Bigazzi, N Wong, F Boschini… - International journal of …, 2015 - Elsevier
To achieve an efficient lung delivery and efficacy, both active ingredient aerosolisation
properties and permeability through the lung need to be optimized. To overcome these …
properties and permeability through the lung need to be optimized. To overcome these …
[PDF][PDF] The effect of carrier particle size on adhesion, content uniformity and inhalation performance of budesonide using dry powder inhalers
Dry Powder Inhalers (DPIs) are the result of the development of two technologies: powder
technology and device technology. Particle deposition in the respiratory tract is affected by …
technology and device technology. Particle deposition in the respiratory tract is affected by …
Engineering pharmaceutical fine particles of budesonide for dry powder inhalation (DPI)
TT Hu, H Zhao, LC Jiang, Y Le, JF Chen… - Industrial & engineering …, 2008 - ACS Publications
Budesonide, as one of the inhaled glucocorticosteroids, is widely used in the treatment of
asthma by pulmonary delivery. The purpose of this study was to prepare ultra-fine …
asthma by pulmonary delivery. The purpose of this study was to prepare ultra-fine …
Engineering drug ultrafine particles of beclomethasone dipropionate for dry powder inhalation
LM Xu, QX Zhang, Y Zhou, H Zhao, JX Wang… - International journal of …, 2012 - Elsevier
Beclomethasone dipropionate (BDP), which is a member in the inhaled glucocorticosteroid
class, is commonly used in the treatment of asthma by pulmonary delivery. The purpose of …
class, is commonly used in the treatment of asthma by pulmonary delivery. The purpose of …
Effect of processing history on the surface interfacial properties of budesonide in carrier-based dry-powder inhalers
J Shur, C Pitchayajittipong, P Rogueda… - Therapeutic …, 2013 - Taylor & Francis
Influence of air-jet micronization, post-micronization conditioning and storage on the surface
properties of budesonide in dry-powder inhaler formulations was investigated. Crystalline …
properties of budesonide in dry-powder inhaler formulations was investigated. Crystalline …
Coated particle assemblies for the concomitant pulmonary administration of budesonide and salbutamol sulphate
J Raula, A Rahikkala, T Halkola, J Pessi… - International journal of …, 2013 - Elsevier
The aims were to prepare stable and well-dispersible pulmonary fine powders composed of
combination drugs with different water solubility, to facilitate concomitant release of …
combination drugs with different water solubility, to facilitate concomitant release of …
[HTML][HTML] Dual functional pullulan-based spray-dried microparticles for controlled pulmonary drug delivery
HY Li, EY Xu - International Journal of Pharmaceutics, 2023 - Elsevier
Two main challenges are associated with current spray-dried microparticles for inhalation,
including the enhancement of aerosolization performance of microparticles and the creation …
including the enhancement of aerosolization performance of microparticles and the creation …
Inhalable microspheres with hierarchical pore size for tuning the release of biotherapeutics in lungs
A series of customized inhalable mono-dispersed poly-L-lactide microspheres (PLA-MS)
having hierarchical pore structures with either open or closed porosity were synthesized by …
having hierarchical pore structures with either open or closed porosity were synthesized by …
Improving Inhalation Performance with Particle Agglomeration via Combining Mechanical Dry Coating and Ultrasonic Vibration
Agglomerate formulations for dry powder inhalation (DPI) formed with fine particles are
versatile means for the highly efficient delivery of budesonide. However, uncontrolled …
versatile means for the highly efficient delivery of budesonide. However, uncontrolled …
[HTML][HTML] Pulmonary targeting of levofloxacin using microsphere-based dry powder inhalation
The objective of the current study was to develop poly (lactic-co-glycolic acid)(PLGA)
microspheres loaded with the anti-tuberculosis (anti-TB) fluoroquinolone, Levofloxacin …
microspheres loaded with the anti-tuberculosis (anti-TB) fluoroquinolone, Levofloxacin …