In this study, we prepared carrier-based formulations for dry powder inhalers by mixing
bosentan microparticles with carrier, prepared in three separate types of lactose. Spray …

Two different types of dry powder inhalers (Easyhaler® and RS01®) were used in this work
to evaluate the ex vivo and in vitro performance of a budesonide inhaled formulation with …

As inhaler design is rarely studied but critically important in pulmonary drug delivery, this
study investigated the influence of inhaler designs, including a novel spiral channel …

The potential of fine excipient materials to improve the aerodynamic performance of carrier-
based dry powder inhalation (DPI) formulations is well acknowledged but not fully …

Efficient delivery of drug particles to the respiratory tract determines therapeutic efficiency of
pulmonary drugs. Only particles with an aerodynamic diameter (d ae) below five …

The aim of this work was to investigate the mechanistic evaluation of physicochemical
properties of new engineered lactose on aerosolisation performance of salbutamol sulphate …

The efficiency of drug delivery from drug-carrier dry powder inhaler (DPI) systems is typically
low. The purpose of this study was to examine the aerosolization performance of a …

Chronic obstructive pulmonary disease (COPD) is a complex disease, characterized by
persistent airflow limitation and chronic inflammation. The purpose of this study was to …

Inhalation drug administration is increasingly used for local pharmacotherapy of lung
disorders and as an alternative route for systemic drug delivery. Modern inhalation powder …

METHODS The fine particle fraction (FPF;% of drug< 4.7 microns) was determined using the
Next Generation Impactor (NGI). UDB (0.135 mg/1.5 mL, UDB 0.250 mg/1.5 mL) was …