A paradigm shift in the management of depression has transpired in recent years with the
modification of treatment goals toward remission, an outcome that transcends response …

Treatment-resistant depression is commonly encountered by mental health professionals.
This is accounted for, in part, by the referral of resistant patients for treatment. But, in …

All definitions of treatment-resistant depression (TRD) require that patients have
experienced insufficient benefit from one or more adequate antidepressant trials. Thus …

ALTHOUGH their pri-mary concerns were the safety and ethics of placebo use, Khan et al1
also used the Food and Drug Administration files on second-generation antidepressants to …

Treatment-resistant depression (TRD) typically refers to inadequate response to at least one
antidepressant trial of adequate doses and duration. TRD is a relatively common occurrence …

The concept of treatment-resistant or treatment-refractory depression (TRD) has evolved
over 40 years since the recognition that some patients minimally benefit from repeated …

Defining Remission in Patients Treated With Antidepressants Page 1 3 J Clin Psychiatry
1999;60 (suppl 22) Introduction © Copyright 2000 Physicians Postgraduate Press, Inc. One …

Switching Antidepressant Class Does Not Improve Response or... : Journal of Clinical
Psychopharmacology Switching Antidepressant Class Does Not Improve Response or …

Previous courses of antidepressant treatment have been related to subsequent decrements
in medication response. The Sequenced Treatment Alternatives to Relieve Depression Trial …

Reportedly, Yogi Berra once said,''If I hadn't believed it, I wouldn't have seen it.''Beneath the
wit lies keen insight: The probability of seeing desired results exceeds the likelihood of …