Comparison of normal and pre-eclamptic placental gene expression: a systematic review with meta-analysis
O Brew, MHF Sullivan, A Woodman - PloS one, 2016 - journals.plos.org
Pre-eclampsia (PE) is a serious multi-factorial disorder of human pregnancy. It is associated
with changes in the expression of placental genes. Recent transcription profiling of placental …
with changes in the expression of placental genes. Recent transcription profiling of placental …
Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia
L Ji, J Brkić, M Liu, G Fu, C Peng, YL Wang - Molecular aspects of medicine, 2013 - Elsevier
The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …
development of the fetus. During human placental development, trophoblast cells …
Differential placental methylation and expression of VEGF, FLT- 1 and KDR genes in human term and preterm preeclampsia
DP Sundrani, US Reddy, AA Joshi, SS Mehendale… - Clinical …, 2013 - Springer
Background Preeclampsia, a pregnancy complication of placental origin is associated with
altered expression of angiogenic factors and their receptors. Recently, there is considerable …
altered expression of angiogenic factors and their receptors. Recently, there is considerable …
Epigenetics and the placenta
ECM Nelissen, APA van Montfoort… - Human reproduction …, 2011 - academic.oup.com
BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …
[HTML][HTML] Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology …
Preeclampsia is a syndromic disease of the mother, fetus, and placenta. The main limitation
in early and accurate diagnosis of preeclampsia is rooted in the heterogeneity of this …
in early and accurate diagnosis of preeclampsia is rooted in the heterogeneity of this …
Gene expression profiling of pre-eclamptic placentae by RNA sequencing
T Kaartokallio, A Cervera, A Kyllönen, K Laivuori… - Scientific reports, 2015 - nature.com
Pre-eclampsia is a common and complex pregnancy disorder that often involves impaired
placental development. In order to identify altered gene expression in pre-eclamptic …
placental development. In order to identify altered gene expression in pre-eclamptic …
[HTML][HTML] Two distinct molecular faces of preeclampsia revealed by single-cell transcriptomics
I Admati, N Skarbianskis, H Hochgerner, O Ophir… - Med, 2023 - cell.com
Introduction Preeclampsia is a multisystemic, pregnancy-specific disorder united by new-
onset hypertension but with considerable variation in clinical manifestation, onset, and …
onset hypertension but with considerable variation in clinical manifestation, onset, and …
Altered global gene expression in first trimester placentas of women destined to develop preeclampsia
SA Founds, YP Conley, JF Lyons-Weiler, A Jeyabalan… - Placenta, 2009 - Elsevier
BACKGROUND: Preeclampsia is a pregnancy-specific disorder that remains a leading
cause of maternal, fetal and neonatal morbidity and mortality, and is associated with risk for …
cause of maternal, fetal and neonatal morbidity and mortality, and is associated with risk for …
The origins and end-organ consequence of pre-eclampsia
G Eastabrook, M Brown, I Sargent - Best Practice & Research Clinical …, 2011 - Elsevier
Pre-eclampsia is a multisystem disorder with profound implications for both mother and
fetus. Its origins lie in the earliest stages of pregnancy. Abnormal interactions between fetal …
fetus. Its origins lie in the earliest stages of pregnancy. Abnormal interactions between fetal …
Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia
Pre-eclampsia is a serious complication of pregnancy that can affect both maternal and fetal
outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is …
outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is …