Introduction: The absorption of poorly water-soluble drugs, when presented in the crystalline
state to the gastrointestinal tract, is typically dissolution rate-limited, and according to BCS …

Introduction: Inhaled drugs are important in the treatment of many lung pathologies, but to be
therapeutically effective they must reach unbound concentrations at their effect site in the …

Purpose To establish an in vivo-relevant Transwell dish-based dissolution test system for the
“respirable” aerosols of inhaled corticosteroids (ICSs) using marketed inhaler products …

The dissolution of powder drugs, besides being a topic of utmost importance, especially for
the sparingly soluble ones, is far from being well-explained. The purpose of the present …

This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …

Flow-through cell dissolution method was implemented in pharmacopoeias in 1990 and
since that time its usage significantly increased. It is employed in oral dosage forms with …