Long noncoding RNAs: new players in the molecular mechanism for maintenance and differentiation of pluripotent stem cells
Maintenance of the pluripotent state or differentiation of the pluripotent state into any germ
layer depends on the factors that orchestrate expression of thousands of genes through …
layer depends on the factors that orchestrate expression of thousands of genes through …
Long non‐coding RNAs in stem cell pluripotency
SY Ng, LW Stanton - Wiley Interdisciplinary Reviews: RNA, 2013 - Wiley Online Library
Pluripotency refers to the self‐renewal of undifferentiated embryonic stem cells (ESCs), and
is maintained by a tightly regulated gene regulatory network involving an intricate interplay …
is maintained by a tightly regulated gene regulatory network involving an intricate interplay …
Long noncoding RNAs in human stemness and differentiation
There is increasing evidence that long noncoding RNAs (lncRNAs) are among the main
regulatory factors of stem cell maintenance and differentiation. They act through various …
regulatory factors of stem cell maintenance and differentiation. They act through various …
Long noncoding RNA regulation of pluripotency
A Rosa, M Ballarino - Stem Cells International, 2016 - Wiley Online Library
Pluripotent stem cells (PSCs) represent a unique kind of stem cell, as they are able to
indefinitely self‐renew and hold the potential to differentiate into any derivative of the three …
indefinitely self‐renew and hold the potential to differentiate into any derivative of the three …
LncRNA functions as a new emerging epigenetic factor in determining the fate of stem cells
J Chen, Y Wang, C Wang, JF Hu, W Li - Frontiers in genetics, 2020 - frontiersin.org
Pluripotent stem cells have broad applications in regenerative medicine and offer ideal
models for understanding the biological process of embryonic development and specific …
models for understanding the biological process of embryonic development and specific …
Regulatory non-coding RNAs in pluripotent stem cells
A Rosa, AH Brivanlou - International journal of molecular sciences, 2013 - mdpi.com
The most part of our genome encodes for RNA transcripts are never translated into proteins.
These include families of RNA molecules with a regulatory function, which can be arbitrarily …
These include families of RNA molecules with a regulatory function, which can be arbitrarily …
Long non-coding RNA in stem cell pluripotency and lineage commitment: functions and evolutionary conservation
LncRNAs have recently emerged as new and fundamental transcriptional and post-
transcriptional regulators acting at multiple levels of gene expression. Indeed, lncRNAs …
transcriptional regulators acting at multiple levels of gene expression. Indeed, lncRNAs …
Human long noncoding RNA regulation of stem cell potency and differentiation
S Lee, HH Seo, CY Lee, J Lee, S Shin… - Stem Cells …, 2017 - Wiley Online Library
Because of their capability of differentiation into lineage‐specific cells, stem cells are an
attractive therapeutic modality in regenerative medicine. To develop an effective stem cell …
attractive therapeutic modality in regenerative medicine. To develop an effective stem cell …
The functions of microRNAs and long non-coding RNAs in embryonic and induced pluripotent stem cells
W Jia, W Chen, J Kang - Genomics, proteomics & bioinformatics, 2013 - academic.oup.com
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) hold immense
promise for regenerative medicine due to their abilities to self-renew and to differentiate into …
promise for regenerative medicine due to their abilities to self-renew and to differentiate into …
Long noncoding RNAs: insights from biological features and functions to diseases
X Li, Z Wu, X Fu, W Han - Medicinal research reviews, 2013 - Wiley Online Library
Over the past decade, genome‐wide transcriptomic studies have shown that the mammalian
genome is pervasively transcribed and produces many thousands of transcriptomes without …
genome is pervasively transcribed and produces many thousands of transcriptomes without …