Genome-wide analysis of microbial pathogens and molecular pathogenesis processes has
become an area of considerable activity in the last 5 years. These studies have been made …

Streptococcus pyogenes (S. pyogenes) and Streptococcus dysgalactiae subspecies
equisimilis (SDSE) cause considerable morbidity and mortality, and show similarities in …

Identification of viridans group streptococci (VGS) to the species level is difficult because
VGS exchange genetic material. We performed multilocus DNA target sequencing to assess …

Many human pathogens produce phenotypic variants as a means to circumvent the host
immune system and enhance survival and, as a potential consequence, exhibit increased …

Streptococcus mutans, known to be an aetiologic agent of dental caries, also causes
infective endocarditis (IE), although a comparison of isolates from the oral cavity and …

Streptococcus sanguinis is a member of the viridans group of streptococci and a leading
cause of the life-threatening endovascular disease infective endocarditis. Initial contact with …

To identify streptococcal genes that are expressed during experimental endocarditis, we
developed a promoter-less dual reporter gene-fusion (amy, cat) plasmid, pAK36 …

The phylogenetic profile of a gene is a reflection of its evolutionary history and can be
defined as the differential presence or absence of a gene in a set of reference genomes. It …

From a common ancestor, Streptococcus pneumoniae and Streptococcus mitis evolved in
parallel into one of the most important pathogens and a mutualistic colonizer of humans …

Group A Streptococcus (GAS) causes an exceptionally broad range of infections in humans,
from relatively mild pharyngitis and skin infections to life-threatening necrotizing fasciitis and …