Clinical and molecular aspects of iron metabolism in failing myocytes
B Kozłowska, B Sochanowicz, L Kraj, M Palusińska… - Life, 2022 - mdpi.com
Heart failure (HF) is a common disease that causes significant limitations on the organism's
capacity and, in extreme cases, leads to death. Clinically, iron deficiency (ID) plays an …
capacity and, in extreme cases, leads to death. Clinically, iron deficiency (ID) plays an …
[HTML][HTML] Role of iron metabolism in heart failure: From iron deficiency to iron overload
H Zhang, P Zhabyeyev, S Wang, GY Oudit - Biochimica et Biophysica Acta …, 2019 - Elsevier
Iron metabolism is a balancing act, and biological systems have evolved exquisite
regulatory mechanisms to maintain iron homeostasis. Iron metabolism disorders are …
regulatory mechanisms to maintain iron homeostasis. Iron metabolism disorders are …
Iron deficiency as therapeutic target in heart failure: a translational approach
C Bakogiannis, A Briasoulis, D Mouselimis… - Heart failure …, 2020 - Springer
Heart failure (HF) is a potentially debilitating condition, with a prognosis comparable to many
forms of cancer. It is often complicated by anemia and iron deficiency (ID), which have been …
forms of cancer. It is often complicated by anemia and iron deficiency (ID), which have been …
[HTML][HTML] Why is iron deficiency recognised as an important comorbidity in heart failure?
N Ebner, S von Haehling - Cardiac Failure Review, 2019 - ncbi.nlm.nih.gov
There is an increasing awareness of the prevalence of iron deficiency in patients with heart
failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace …
failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace …
Identification of three mechanistic pathways for iron-deficient heart failure
Current understanding of iron-deficient heart failure is based on blood tests that are thought
to reflect systemic iron stores, but the available evidence suggests greater complexity. The …
to reflect systemic iron stores, but the available evidence suggests greater complexity. The …
Influence of mitochondrial and systemic iron levels in heart failure pathology
Iron deficiency or overload poses an increasingly complex issue in cardiovascular disease,
especially heart failure. The potential benefits and side effects of iron supplementation are …
especially heart failure. The potential benefits and side effects of iron supplementation are …
Iron deficiency in heart failure: mechanisms and pathophysiology
RIS Alnuwaysir, MF Hoes, DJ van Veldhuisen… - Journal of clinical …, 2021 - mdpi.com
Iron is an essential micronutrient for a myriad of physiological processes in the body beyond
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …
Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives
EA Jankowska, S von Haehling, SD Anker… - European heart …, 2013 - academic.oup.com
Iron is a micronutrient essential for cellular energy and metabolism, necessary for
maintaining body homoeostasis. Iron deficiency is an important co-morbidity in patients with …
maintaining body homoeostasis. Iron deficiency is an important co-morbidity in patients with …
Iron deficiency in myocardial ischaemia: molecular mechanisms and therapeutic perspectives
F Corradi, G Masini, T Bucciarelli… - Cardiovascular …, 2023 - academic.oup.com
Systemic iron deficiency (SID), even in the absence of anaemia, worsens the prognosis and
increases mortality in heart failure (HF). Recent clinical–epidemiological studies, however …
increases mortality in heart failure (HF). Recent clinical–epidemiological studies, however …
[HTML][HTML] Chronic heart failure: clinical implications of iron homeostasis disturbances revisited
Iron deficiency is prevalent in chronic heart failure (CHF) patients. Nonetheless, the
diagnosis is often overlooked and, often, the treatment is commenced just when overt …
diagnosis is often overlooked and, often, the treatment is commenced just when overt …