The aim of this research project was to investigate a potential standardized test method to
characterize the dissolution properties of numerous formulation types available for …

Pulmonary dissolution of poorly soluble drug substances (DSs) may limit the drug
absorption rate and consequently influence clinical performance. Dissolution rate is thus an …

Dry powder inhalation therapy has been effective in treating localized lung diseases such
asthma, chronic obstructive pulmonary diseases (COPD), cystic fibrosis and lung infections …

The aim of this study was the development and evaluation of a miniaturized setup for in vitro
dissolution testing of inhalation powders based on an adapted Transwell system with …

The pulmonary route of administration is used for both locally and systemically acting drugs.
However, knowledge gaps about the fate of aerosol particles after deposition in the lung …

This chapter describes several approaches that have been developed for the
characterization and understanding of the dissolution in the lung environment. Inhalation …

Dissolution testing is routinely used for quality control purposes to test batch‐to‐batch
consistency, stability and detect manufacturing deviations of pharmaceutical products. While …

The aim of the study was to develop a robust and standardized in vitro dissolution
methodology for orally inhaled drug products (OIDPs). An aerosol dose collection (ADC) …

Correlating data from in vitro dissolution testing of inhaled particulate pharmaceuticals or air
pollutants with the dissolution and distribution to the blood circulation of the same aerosols …