Background: The performance of carrier-based dry powder inhalation formulations strongly
depends on particle interactions between the drug and the carrier. Among other factors like …

Although dry powder inhalers (DPIs) have attracted great interest compared to nebulizers
and metered-dose inhalers (MDIs), drug deposition in the deep lung is still insufficient to …

Solution composition alters the dynamics of beclomethasone diproprionate (BDP) particle
formation from droplets emitted by pressurised metered dose inhalers (pMDIs). The …

It has long been desired to match airflow conditions during formulation evaluation to those of
relevance to lung deposition. In this context several strategies have been adopted involving …

Glucocorticoids administered by inhalation remain a first-line treatment of patients with
asthma allergic rhinitis and advanced chronic obstructive pulmonary disease. Budesonide …

One of the simplest design concepts of inhaled sustained drug delivery to the lung is to
utilize the slow dissolution of drug crystals with poor aqueous solubility. An optimum …

Dry Powder Inhalers play a major role in today's treatment of various respiratory diseases. A
lot of effort has been put into the optimization of a device and the appropriate formulation …

The isolated, perfused rat lung preparation was modified to allow characterized solid
aerosol delivery. Deposition and airway‐to‐perfusate transfer of disodium fluorescein from 3 …

For many years, administration of drugs by inhalation has been the mainstay treatment for
obstructive respiratory disorders such as asthma and chronic obstructive pulmonary …

In vitro dissolution testing as a form of quality control has become a necessity in the
pharmaceutical industry. As such, the need to establish a method that investigates the in …