Asthma is a serious global health problem with rising prevalence and treatment costs. Due
to the growing number of different types of inhalation devices and aerosol drugs, physicians …

Interactions between drug particulates are crucial in determining drug dispersion and
deaggregation, and ultimately delivery efficiency. This book combines principles established …

Dry powders and their delivery devices are an alternative to pressurized metered-dose
inhalers (pMDI) for the administration of aerosols to the lungs. Generally dry powder …

Though various attempts have been made in literature to model the particle size distribution
of an active pharmaceutical ingredient (API) in function of the required release profile of the …

Background: A new in vitro test method for dry powder inhalers (DPIs) was recently found to
be predictive of the published in vivo results for Budelin Novolizer. The present study was …

The relationship between surface coverage and in vitro respirable fraction—often referred to
as fine particle fraction (FPF)—of dry powder inhaler (DPI) formulations for the therapy of …

There is plenty of evidence supporting the notion that the size of the carrier influences the
aerosolisation performance of drug from a drug–carrier blend. Interestingly, that evidence is …

Research on pharmaceutical dry powders has been increasing worldwide, along with
increased therapeutic strategies for an application through the pulmonary or the nasal …

The effect of carrier surface properties on drug particle detachment from carrier crystals
during inhalation with a special test inhaler with basic air classifier has been studied for …

Besides deposition, pulmonary bioavailability is determined by dissolution of particles in the
scarce epithelial fluid and by cellular API uptake. In the present work, we have developed an …